Alternative splicing and related RNA binding proteins in human health and disease
Y Tao, Q Zhang, H Wang, X Yang, H Mu - Signal Transduction and …, 2024 - nature.com
Alternative splicing (AS) serves as a pivotal mechanism in transcriptional regulation,
engendering transcript diversity, and modifications in protein structure and functionality …
engendering transcript diversity, and modifications in protein structure and functionality …
Alternative splicing, an Overlooked Defense Frontier of Plants with respect to bacterial infection
JQ Xie, X Zhou, ZC Jia, CF Su, Y Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Disease represents a major problem in sustainable agricultural development. Plants interact
closely with various microorganisms during their development and in response to the …
closely with various microorganisms during their development and in response to the …
Deregulated microRNAs involved in prostate cancer aggressiveness and treatment resistance mechanisms
Simple Summary Accumulating studies have highlighted the critical roles of microRNAs in
tumorigenesis and cancer treatment responses. Here, we systematically review the scientific …
tumorigenesis and cancer treatment responses. Here, we systematically review the scientific …
Osteopontin and cancer: insights into its role in drug resistance
C Hao, J Lane, WG Jiang - Biomedicines, 2023 - mdpi.com
Cancer is one of the leading causes of mortality worldwide. Currently, drug resistance is the
main obstacle in cancer treatments with the underlying mechanisms of drug resistance yet to …
main obstacle in cancer treatments with the underlying mechanisms of drug resistance yet to …
[HTML][HTML] The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer
M Liu, S Zhang, H Zhou, X Hu, J Li, B Fu, M Wei… - Theranostics, 2023 - ncbi.nlm.nih.gov
Alternative splicing (AS) is a common and conserved process in eukaryotic gene regulation.
It occurs in approximately 95% of multi-exon genes, greatly enriching the complexity and …
It occurs in approximately 95% of multi-exon genes, greatly enriching the complexity and …
Competing endogenous RNA (ceRNA) networks and splicing switches in cervical cancer: HPV oncogenesis, clinical significance and therapeutic opportunities
Cervical cancer (CC) is the primary cause of female cancer fatalities in low-middle-income
countries (LMICs). Persistent infections from the human papillomavirus (HPV) can result in …
countries (LMICs). Persistent infections from the human papillomavirus (HPV) can result in …
Chemotherapeutic drug resistance associated with differential miRNA expression of miR-375 and miR-27 among oral cancer cell lines
KC Huni, J Cheung, M Sullivan, WT Robison… - International Journal of …, 2023 - mdpi.com
Recent advances have suggested that non-coding miRNAs (such as miR-21, miR-27, miR-
145, miR-155, miR-365, miR-375 and miR-494) may be involved in multiple aspects of oral …
145, miR-155, miR-365, miR-375 and miR-494) may be involved in multiple aspects of oral …
Upregulation of miRNA-10a-5p promotes tumor progression in cervical cancer by suppressing UBE2I signaling
Y Gu, X Feng, Y Jin, Y Liu, L Zeng… - Journal of Obstetrics …, 2023 - Taylor & Francis
Cervical cancer (CC) is a common malignant neoplasm in gynecology. There is increasing
evidence to suggest that microRNAs (miRNAs) act as crucial regulators of CC. However …
evidence to suggest that microRNAs (miRNAs) act as crucial regulators of CC. However …
Targeted splicing therapy: new strategies for colorectal cancer
Y Zheng, G Zhong, C He, M Li - Frontiers in Oncology, 2023 - frontiersin.org
RNA splicing is the process of forming mature mRNA, which is an essential phase
necessary for gene expression and controls many aspects of cell proliferation, survival, and …
necessary for gene expression and controls many aspects of cell proliferation, survival, and …
RNA-Binding Proteins as Epigenetic Regulators of Brain Functions and Their Involvement in Neurodegeneration
CM Di Liegro, G Schiera, G Schirò… - International Journal of …, 2022 - mdpi.com
A central aspect of nervous system development and function is the post-transcriptional
regulation of mRNA fate, which implies time-and site-dependent translation, in response to …
regulation of mRNA fate, which implies time-and site-dependent translation, in response to …