[PDF][PDF] Circuit mechanisms of Parkinson's disease

MM McGregor, AB Nelson - Neuron, 2019 - cell.com
Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …

Parkinson's disease dementia: a neural networks perspective

J Gratwicke, M Jahanshahi, T Foltynie - Brain, 2015 - academic.oup.com
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

[HTML][HTML] Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating

RS Shivacharan, CE Rolle, DAN Barbosa… - Nature medicine, 2022 - nature.com
Cravings that precede loss of control (LOC) over food consumption present an opportunity
for intervention in patients with the binge eating disorder (BED). In this pilot study, we used …

[HTML][HTML] Not all brains are created equal: the relevance of individual differences in responsiveness to transcranial electrical stimulation

B Krause, R Cohen Kadosh - Frontiers in systems neuroscience, 2014 - frontiersin.org
A current issue in the research of augmentation of brain functions using transcranial
electrical stimulation (tES) is the diversity and inconsistency in outcome results. Similar …

[HTML][HTML] Dynamic network communication as a unifying neural basis for cognition, development, aging, and disease

B Voytek, RT Knight - Biological psychiatry, 2015 - Elsevier
Perception, cognition, and social interaction depend upon coordinated neural activity. This
coordination operates within noisy, overlapping, and distributed neural networks operating …

[HTML][HTML] Tuning pathological brain oscillations with neurofeedback: a systems neuroscience framework

T Ros, B J. Baars, RA Lanius… - Frontiers in human …, 2014 - frontiersin.org
Neurofeedback (NFB) is emerging as a promising technique that enables self-regulation of
ongoing brain oscillations. However, despite a rise in empirical evidence attesting to its …

Neuromodulation for brain disorders: challenges and opportunities

MD Johnson, HH Lim, TI Netoff… - IEEE Transactions …, 2013 - ieeexplore.ieee.org
The field of neuromodulation encompasses a wide spectrum of interventional technologies
that modify pathological activity within the nervous system to achieve a therapeutic effect …

[HTML][HTML] Deep brain stimulation for movement disorders of basal ganglia origin: restoring function or functionality?

T Wichmann, MR DeLong - Neurotherapeutics, 2016 - Elsevier
Deep brain stimulation (DBS) is highly effective for both hypo-and hyperkinetic movement
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …

Bilateral deep brain stimulation of the nucleus basalis of Meynert for Parkinson disease dementia: a randomized clinical trial

J Gratwicke, L Zrinzo, J Kahan, A Peters, M Beigi… - JAMA …, 2018 - jamanetwork.com
Importance Deep brain stimulation of the nucleus basalis of Meynert (NBM DBS) has been
proposed as a treatment option for Parkinson disease dementia. Objective To evaluate the …

Frequency-specific optogenetic deep brain stimulation of subthalamic nucleus improves parkinsonian motor behaviors

C Yu, IR Cassar, J Sambangi… - Journal of Neuroscience, 2020 - Soc Neuroscience
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for the
motor symptoms of Parkinson's disease (PD). However, the neural elements mediating …