Primary brain tumours in adults
The most frequent adult-type primary CNS tumours are diffuse gliomas, but a large variety of
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …
PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0): a report of the RANO group
Summary Response Assessment in Neuro-Oncology (RANO) response criteria have been
established and were updated in 2023 for MRI-based response evaluation of diffuse …
established and were updated in 2023 for MRI-based response evaluation of diffuse …
[HTML][HTML] Mitochondria deregulations in cancer offer several potential targets of therapeutic interventions
C Musicco, A Signorile, V Pesce… - International Journal of …, 2023 - mdpi.com
Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …
[HTML][HTML] Precision oncology: 2023 in review
YR Murciano-Goroff, SP Suehnholz, A Drilon… - Cancer Discovery, 2023 - AACR
This article presents a review of recent major advances in precision oncology and the future
implications of these advances, specifying the iterative progress achieved from the end of …
implications of these advances, specifying the iterative progress achieved from the end of …
[HTML][HTML] Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma
M Weller, J Felsberg, B Hentschel, D Gramatzki… - Acta …, 2024 - Springer
Prognostic factors and standards of care for astrocytoma, isocitrate dehydrogenase (IDH)-
mutant, CNS WHO grade 4, remain poorly defined. Here we sought to explore disease …
mutant, CNS WHO grade 4, remain poorly defined. Here we sought to explore disease …
[HTML][HTML] Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas
E Blanco-Carmona, A Narayanan, I Hernandez… - Cell Reports …, 2023 - cell.com
The isocitrate dehydrogenase (IDH) gene is recurrently mutated in adult diffuse gliomas. IDH-
mutant gliomas are categorized into oligodendrogliomas and astrocytomas, each with …
mutant gliomas are categorized into oligodendrogliomas and astrocytomas, each with …
The surgical management of diffuse gliomas: Current state of neurosurgical management and future directions
After recent updates to the World Health Organization pathological criteria for diagnosing
and grading diffuse gliomas, all major North American and European neuro-oncology …
and grading diffuse gliomas, all major North American and European neuro-oncology …
Tumor volume growth rates and doubling times during active surveillance of IDH-mutant low-grade glioma
Purpose: Isocitrate dehydrogenase–mutant (IDH-mt) gliomas are incurable primary brain
tumors characterized by a slow-growing phase over several years followed by a rapid …
tumors characterized by a slow-growing phase over several years followed by a rapid …
Molecular profiling and targeted therapies in gliomas
Y Felistia, PY Wen - Current Neurology and Neuroscience Reports, 2023 - Springer
Abstract Purpose of Review Molecular profiling enables the evaluation of genetic alterations
for the diagnosis and classification of gliomas and the selection of appropriate therapies …
for the diagnosis and classification of gliomas and the selection of appropriate therapies …
[HTML][HTML] Immunotherapy approaches in isocitrate-dehydrogenase-mutant low-grade glioma
Simple Summary IDH-mutant low-grade gliomas (LGG) are slow-growing glial cell-derived
tumors of the central nervous system (CNS) that predominantly manifest in young adults and …
tumors of the central nervous system (CNS) that predominantly manifest in young adults and …