To understand how function arises from the interactions between neurons, it is necessary to
use methods that allow the monitoring of brain activity at the single-neuron, single-spike …

The evolution of the field of neuroscience has been propelled by the advent of novel
technological capabilities, and the pace at which these capabilities are being developed has …

GABA interneurons play a critical role in higher brain functions. Astrocytic glial cells interact
with synapses throughout the whole brain and are recognized as regulatory elements of …

Theta-gamma phase coupling and spike timing within theta oscillations are prominent
features of the hippocampus and are often related to navigation and memory. However, the …

The consolidation of context-dependent emotional memory requires communication
between the hippocampus and the basolateral amygdala (BLA), but the mechanisms of this …

Sleep exerts many effects on mammalian forebrain networks, including homeostatic effects
on both synaptic strengths and firing rates. We used large-scale recordings to examine the …

Many neurological and psychiatric diseases are associated with clinically detectable, altered
brain dynamics. The aberrant brain activity, in principle, can be restored through electrical …

Sensory cue inputs and memory-related internal brain activities govern the firing of
hippocampal neurons, but which specific firing patterns are induced by either of the two …

Cell assembly sequences during learning are “replayed” during hippocampal ripples and
contribute to the consolidation of episodic memories. However, neuronal sequences may …

Monitoring representative fractions of neurons from multiple brain circuits in behaving
animals is necessary for understanding neuronal computation. Here, we describe a system …