Cancer is the principal cause of death and a dominant public health problem which
seriously threatening human life. Among various ways to treat cancer, traditional Chinese …

Cardiotoxicity is the main concern for long‐term use of the doxorubicin (DOX). Reactive
oxygen species (ROS) generation leads to oxidative stress that significantly contributes to …

Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease.
Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin …

Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-
induced acute liver injury and the underlying molecular mechanisms. Mice were orally …

The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …

Background Mitochondria, the power plants of the cell, are known as a cross-road of
different cellular signaling pathways. These cytoplasmic double-membraned organelles play …

Abstract Blocking the PD-L1/PD-1 pathway to prevent the immune evasion of tumor cells is a
powerful approach for treating multiple cancers, including hepatocellular carcinoma (HCC) …

In recent times, neurodegenerative diseases are the most challenging global health
problems. Neuronal cell death or damage is a key factor for many neurodegenerative …

Neurodegenerative diseases are a heterogeneous group of disorders that are characterized
by the gradual loss of neurons. The development of effective neuroprotective agents to …