Osteoporosis is a skeletal disorder that causes impairment of bone structure and strength,
leading to a progressively increased risk of fragility fractures. The global prevalence of …

The adult skeleton regenerates by temporary cellular structures that comprise teams of
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …

Many studies have shown cross-sectional (and two small studies, longitudinal) declines in
total and/or free testosterone (T) levels, with age, in men. The extent to which decline in T is …

The still‐evolving mechanostat hypothesis for bones inserts tissue‐level realities into the
former knowledge gap between bone's organ‐level and cell‐level realities. It concerns load …

Understanding how bones are innately designed, robustly developed and delicately
maintained through intricate anatomical features and physiological processes across the …

Porous and functionally graded materials have seen extensive applications in modern
biomedical devices—allowing for improved site-specific performance; their appreciable …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Sex steroids are chief regulators of gender differences in the skeleton, and male gender is
one of the strongest protective factors against osteoporotic fractures. This advantage in bone …

Most estimates of osteoporosis in older US adults have been based on its occurrence in
white women, even though it is known to affect men and minority women. In the present …

Estrogen (E) deficiency associated with the menopause is the major cause of bone loss in
aging women. However, men also lose significant amounts of bone with age, but they do not …