[HTML][HTML] Role of stress in skin diseases: a neuroendocrine-immune interaction view

H Zhang, M Wang, X Zhao, Y Wang, X Chen… - Brain, behavior, and …, 2024 - Elsevier
Psychological stress is a crucial factor in the development of many skin diseases, and the
stigma caused by skin disorders may further increase the psychological burden, forming a …

Targeting tumor innervation: premises, promises, and challenges

X Li, X Peng, S Yang, S Wei, Q Fan, J Liu, L Yang… - Cell death …, 2022 - nature.com
A high intratumoral nerve density is correlated with poor survival, high metastasis, and high
recurrence across multiple solid tumor types. Recent research has revealed that cancer cells …

Sympathetic neurostress drives osteoblastic exosomal MiR‐21 transfer to disrupt bone homeostasis and promote osteopenia

CH Hu, BD Sui, J Liu, L Dang, J Chen… - Small …, 2022 - Wiley Online Library
Innervation and extracellular vesicle secretion co‐exist in the local tissue microenvironment
for message transfer, but whether they are interconnected to regulate organ homeostasis …

The impact of perceived stress on the hair follicle: towards solving a psychoneuroendocrine and neuroimmunological puzzle

JDB O'Sullivan, EMJ Peters, Y Amer, P Atuluru… - Frontiers in …, 2022 - Elsevier
While popular belief harbors little doubt that perceived stress can cause hair loss and
premature graying, the scientific evidence for this is arguably much thinner. Here, we …

Targeting the MR1-MAIT cell axis improves vaccine efficacy and affords protection against viral pathogens

R Rashu, M Ninkov, CM Wardell, JM Benoit… - PLoS …, 2023 - journals.plos.org
Mucosa-associated invariant T (MAIT) cells are MR1-restricted, innate-like T lymphocytes
with tremendous antibacterial and immunomodulatory functions. Additionally, MAIT cells …

Norepinephrine inhibits CD8+ T-cell infiltration and function, inducing anti-PD-1 mAb resistance in lung adenocarcinoma

Q Geng, L Li, Z Shen, Y Zheng, L Wang, R Xue… - British Journal of …, 2023 - nature.com
Background Mental stress-induced neurotransmitters can affect the immune system in
various ways. Therefore, a better understanding of the role of neurotransmitters in the …

Tong-Xie-Yao-Fang promotes dendritic cells maturation and retards tumor growth in colorectal cancer mice with chronic restraint stress

Y Jiang, Y Hu, Y Yang, R Yan, L Zheng, X Fu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Depression is one of the important risk factors that
accelerate the progression of colorectal cancer (CRC). Tong-Xie-Yao-Fang (TXYF) is a …

T cell-mediated skin-brain axis: Bridging the gap between psoriasis and psychiatric comorbidities

J Yang, S Zhang, Q Wu, P Chen, Y Dai, J Long… - Journal of …, 2024 - Elsevier
Psoriasis, a chronic inflammatory skin condition, is often accompanied by psychiatric
comorbidities such as anxiety, depression, suicidal ideation, and other mental disorders …

[HTML][HTML] Impact of chronic stress on intestinal mucosal immunity in colorectal cancer progression

S Yang, Y Li, Y Zhang, Y Wang - Cytokine & Growth Factor Reviews, 2024 - Elsevier
Chronic stress is a significant risk factor that contributes to the progression of colorectal
cancer (CRC) and has garnered considerable attention in recent research. It influences the …

Natural Killer Cells and cytotoxic T cells: complementary partners against microorganisms and Cancer

A Vojdani, S Koksoy, E Vojdani, M Engelman, C Benzvi… - Microorganisms, 2024 - mdpi.com
Natural killer (NK) cells and cytotoxic T (CD8+) cells are two of the most important types of
immune cells in our body, protecting it from deadly invaders. While the NK cell is part of the …