Sex-gender variable: methodological recommendations for increasing scientific value of clinical studies
There is a clear sex–gender gap in the prevention and occurrence of diseases, and in the
outcomes and treatments, which is relevant to women in the majority of cases. Attitudes …
outcomes and treatments, which is relevant to women in the majority of cases. Attitudes …
High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies
Obesity and related metabolic diseases show clear sex-related differences. The growing
burden of these diseases calls for better understanding of the age-and sex-related metabolic …
burden of these diseases calls for better understanding of the age-and sex-related metabolic …
The majority of male patients with COVID-19 present low testosterone levels on admission to Intensive Care in Hamburg, Germany: a retrospective cohort study
M Schroeder, B Tuku, D Jarczak, A Nierhaus, T Bai… - MedRxiv, 2020 - medrxiv.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to
spread worldwide and pose a major public health burden. There is increasing evidence that …
spread worldwide and pose a major public health burden. There is increasing evidence that …
Exposomics as a tool to investigate differences in health and disease by sex and gender
The health and disease of an individual is mediated by their genetics, a lifetime of
environmental exposures, and interactions between the two. Genetic or biological sex …
environmental exposures, and interactions between the two. Genetic or biological sex …
LC/MS-based untargeted metabolomics analysis in women with morbid obesity and associated type 2 diabetes mellitus
Obesity is a chronic and complex disease, with an increasing incidence worldwide that is
associated with metabolic disorders such as type 2 diabetes mellitus (T2DM). Thus, it is …
associated with metabolic disorders such as type 2 diabetes mellitus (T2DM). Thus, it is …
Cooperative p16 and p21 action protects female astrocytes from transformation
N Kfoury, T Sun, K Yu, N Rockwell, KL Tinkum… - Acta neuropathologica …, 2018 - Springer
Mechanisms underlying sex differences in cancer incidence are not defined but likely
involve dimorphism (s) in tumor suppressor function at the cellular and organismal levels. As …
involve dimorphism (s) in tumor suppressor function at the cellular and organismal levels. As …
Metabolomic determinants of metabolic risk in Mexican adolescents
Objective The goal of this study was to identify metabolites associated with metabolic risk,
separately by sex, in Mexican adolescents. Methods Untargeted metabolomic profiling was …
separately by sex, in Mexican adolescents. Methods Untargeted metabolomic profiling was …
Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndrome
Z Mao, T Li, H Zhao, X Wang, Y Kang… - Journal of Cellular …, 2021 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrine diseases of fertile women
and a major cause of infertility. The regulatory effects of DNA methylation on gene …
and a major cause of infertility. The regulatory effects of DNA methylation on gene …
New perspectives on 'Breathomics': metabolomic profiling of non-volatile organic compounds in exhaled breath using DI-FT-ICR-MS
M Malik, T Demetrowitsch, K Schwarz… - Communications …, 2024 - nature.com
Breath analysis offers tremendous potential for diagnostic approaches, since it allows for
easy and non-invasive sample collection.“Breathomics” as one major research field …
easy and non-invasive sample collection.“Breathomics” as one major research field …
Sexual dimorphism in body weight loss, improvements in cardiometabolic risk factors and maintenance of beneficial effects 6 months after a low-calorie diet: Results …
A low-calorie diet (LCD) is an effective strategy to lose weight and improve cardiometabolic
risk factors, however, sexual dimorphism may be present. This study aims to investigate …
risk factors, however, sexual dimorphism may be present. This study aims to investigate …