The role of innate and adaptive immune cells in skeletal muscle regeneration

N Ziemkiewicz, G Hilliard, NA Pullen… - International journal of …, 2021 - mdpi.com
Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide
variety of innate and adaptive immune cells orchestrate the complex process of muscle …

Mesenchymal stromal cells and their secretome: new therapeutic perspectives for skeletal muscle regeneration

M Sandonà, L Di Pietro, F Esposito… - … in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Cell therapy to improve regeneration of skeletal muscle injuries

TH Qazi, GN Duda, MJ Ort, C Perka… - Journal of cachexia …, 2019 - Wiley Online Library
Diseases that jeopardize the musculoskeletal system and cause chronic impairment are
prevalent throughout the Western world. In Germany alone,~ 1.8 million patients suffer from …

Current strategies for the regeneration of skeletal muscle tissue

E Alarcin, A Bal-Öztürk, H Avci, H Ghorbanpoor… - International journal of …, 2021 - mdpi.com
Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal
muscle and lead to functional impairment and severe disability. Skeletal muscle …

Stem cell and macrophage roles in skeletal muscle regenerative medicine

P Scala, L Rehak, V Giudice, E Ciaglia… - International Journal of …, 2021 - mdpi.com
In severe muscle injury, skeletal muscle tissue structure and functionality can be repaired
through the involvement of several cell types, such as muscle stem cells, and innate immune …

Mesenchymal stem/stromal cells and their paracrine activity—immunomodulation mechanisms and how to influence the therapeutic potential

R Alvites, M Branquinho, AC Sousa, B Lopes, P Sousa… - Pharmaceutics, 2022 - mdpi.com
With high clinical interest to be applied in regenerative medicine, Mesenchymal
Stem/Stromal Cells have been widely studied due to their multipotency, wide distribution …

Stem cells for skeletal muscle tissue engineering

MN Pantelic, LM Larkin - Tissue Engineering Part B: Reviews, 2018 - liebertpub.com
Volumetric muscle loss (VML) is a debilitating condition wherein muscle loss overwhelms
the body's normal physiological repair mechanism. VML is particularly common among …

[HTML][HTML] A simple method to isolate and expand human umbilical cord derived mesenchymal stem cells: using explant method and umbilical cord blood serum

G Hassan, I Kasem, C Soukkarieh… - … journal of stem cells, 2017 - synapse.koreamed.org
Methods and Results MSCs were isolated by culturing umbilical cord pieces in CBS or FBS
supplemented media. Expansion and proliferation kinetics of cells isolated by explant …

Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome

X Jiang, J Yang, F Liu, J Tao, J Xu, M Zhang - Stem cell research & …, 2022 - Springer
Background Acute compartment syndrome (ACS), a well-known complication of
musculoskeletal injury, results in muscle necrosis and cell death. Embryonic stem cell …

Long noncoding RNA DANCR regulates miR-1305-Smad 4 axis to promote chondrogenic differentiation of human synovium-derived mesenchymal stem cells

L Zhang, X Sun, S Chen, C Yang, B Shi… - Bioscience …, 2017 - portlandpress.com
miRNAs have been reported to regulate cellular differentiation by modulating multiple
signaling pathways. Long noncoding RNA (lnc RNA) DANCR was previously identified to be …