The electrochemically enabled α-C (sp 3)–H azolation of ketones

S Fang, K Zhong, S Zeng, X Hu, P Sun… - Chemical …, 2023 - pubs.rsc.org
C–H/N–H cross-coupling has become a key technology for the selective conjugation of
azole drug molecules. However, the development of new synthetic models and green …

Ruthenium (II)-Catalyzed Tandem C–H Allylation and [3+ 2] Dipolar Cycloaddition to Construct Bridged Tetracycles

J Moon, N Ko, S Jang, P Ghosh, HS Kim… - Organic …, 2022 - ACS Publications
The ruthenium (II)-catalyzed tandem C–H allylation and intramolecular dipolar cycloaddition
between azomethine imines and 2-methylidenetrimethylene carbonate is described herein …

Covalent Adaptable Networks Made by Reactive Processing of Highly Entangled Polymer: Synthesis-Structure-Thermomechanical Property-Reprocessing …

LM Fenimore, MJ Suazo, JM Torkelson - Macromolecules, 2024 - ACS Publications
Reactive processing provides a simple approach for grafting dynamic covalent cross-linkers
onto linear or branched polymers, resulting in covalent adaptable networks (CANs). We …

Metal-Free Regioselective N2-Arylation of 1H-Tetrazoles with Diaryliodonium Salts

RA Saikia, A Dutta, B Sarma… - The Journal of Organic …, 2022 - ACS Publications
We describe a simple, metal-free regioselective N2-arylation strategy for 5-substituted-1 H-
tetrazoles with diaryliodonium salts to access 2-aryl-5-substituted-tetrazoles. Diaryliodonium …

Synthesis of succinimide-linked indazol-3-ols derived from maleimides under Rh (III) catalysis

JY Kang, S Kim, J Moon, E Chung, J Kim, SY Kyung… - ACS …, 2022 - ACS Publications
The structural modification of N-aryl indazolols as tautomers of N-aryl indazolones has been
established as a hot topic in pharmaceutics and medicinal chemistry. We herein disclose the …

Consecutive cross-dehydrogenative C–O and C–N construction for the synthesis of polyarene with AIE properties under electrochemical condition involving oxygen …

Z Zhang, L Wen, S Xu, Y Tang, X Cao, P Feng - Green Chemistry, 2023 - pubs.rsc.org
A practical and scalable protocol for the regioselective C–H phenoxylation and azolation of
phenol derivatives via consecutive electro-oxidative CDC reaction has been demonstrated …

Assembly of the Hydroxycinnoline Core via Hydrazide-Assisted Rh (III)-Catalyzed C–H Functionalization and Annulation

S Kim, HK Park, JY Kang, NK Mishra, IS Kim - Synthesis, 2022 - thieme-connect.com
The structural modification of phthalazinones and indazolones has emerged as a pivotal
topic in catalytic C–H functionalization events. Herein we report the hydrazide-assisted …

Advances in Palladium-Catalyzed C(sp3)–H Functionalization: The Role of Traceless Directing Groups

M Sadeghi - ACS Catalysis, 2024 - ACS Publications
Selective functionalization of a specific C (sp3)–H bond remains an open challenge in
synthetic chemistry. One common strategy employed by chemists to address this challenge …

Regio- and Enantioselective Construction of Tetrazole Hemiaminal Esters and Related Prodrugs via Biocatalytic Dynamic Kinetic Resolution

M Han, C Liu, X Li, J Jiang, Z Liu… - The Journal of Organic …, 2024 - ACS Publications
Enzyme-catalyzed dynamic kinetic resolution was applied to the one-pot regio-and
enantioselective synthesis of 2, 5-disubstituted tetrazole hemiaminal esters, among which …

Unravelling the factors affecting the stability and reactivity of dehydro-pyrazole, isothiazole and isoxazole radical isomers: a computational study

A Mahadevan, P Kumar, S Butt, A Velloth… - New Journal of …, 2024 - pubs.rsc.org
Reactive open-shell ring systems comprising C, N, O, and S atoms are crucial for the
radiation-induced molecular evolution and relevant to life and interstellar regions. Herein …