Synthesis, characterization, thermal properties, antimicrobial evaluation, ADMET study, and molecular docking simulation of new mono Cu (II) and Zn (II) complexes …

A Ragab, YA Ammar, A Ezzat, AM Mahmoud… - Computers in Biology …, 2022 - Elsevier
One of the interesting research fields is developing and assessing novel metal-containing
medications. A new isatin-3-thiosemicarbazone derivative 4 was synthesized by two …

Novel zinc (II) and copper (II) complexes of 2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde for antibacterial and antioxidant activities: A combined experimental …

T Damena, MB Alem, D Zeleke, T Desalegn… - ACS …, 2022 - ACS Publications
In the present work, two novel complexes of zinc (II) and copper (II) were synthesized from
the ligand 2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde (H 2 L) in a 1: 2 metal-to …

New Ni (II) and Cu (II) Schiff base coordination complexes derived from 5-Bromo-salicylaldehyde and 3-picoyl amine/ethylenediamine: Synthesis, structure, Hirshfeld …

M Choudhary - Polyhedron, 2023 - Elsevier
Two co-ordination compounds, one nickel (II) complex [Ni (L 1)(Phen) 2] ClO 4 (1) and one
copper (II) complex [Cu (L 2)](2), were synthesized using Schiff base ligands derived from …

[HTML][HTML] Synthesis, characterization, and biological activities of zinc (II), copper (II) and nickel (II) complexes of an aminoquinoline derivative

T Damena, MB Alem, D Zeleke, T Desalegn… - Frontiers in …, 2022 - frontiersin.org
Interest is increasingly focused on the use of transition metal complexes as biochemical,
medical, analytical, pharmaceutical, agronomic, anticancer, and antibacterial agents. In this …

[HTML][HTML] Synthesis and characterization of violurate-based Mn (II) and Cu (II) complexes nano-crystallites as DNA-binders and therapeutics agents against SARS-CoV …

SA Al-Harbi - Journal of Saudi Chemical Society, 2022 - Elsevier
Synthesis and structural characterization of nano crystallites of bis-violurate-based
manganese (II) and copper (II) chelates is the subject of the present study. Analytical data …

Synthesis, single-crystal exploration, hirshfeld surface analysis, and DFT investigation of the thiosemicarbazones

M Ashfaq, A Ali, MN Tahir, A Kuznetsov… - Journal of Molecular …, 2022 - Elsevier
Thiosemicarbazones (TSCs) are considered as one of the most significant classes of
organic compounds in recent time due to their applications in pharmaceutical chemistry …

Unusual Ni⋯ Ni interaction in Ni (ii) complexes as potential inhibitors for the development of new anti-SARS-CoV-2 Omicron drugs

S Singh, M Choudhary - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
Two nickel (II) coordination complexes [Ni (L)] 2 (1) and [Ni (L)] n (2) of a tetradentate Schiff
base ligand (H2L) derived from 2-hydroxy-1-naphthaldehyde with ethylenediamine were …

Can iron chelators ameliorate viral infections?

TA Pereira, BP Espósito - BioMetals, 2024 - Springer
The redox reactivity of iron is a double-edged sword for cell functions, being either essential
or harmful depending on metal concentration and location. Deregulation of iron homeostasis …

New nickel (II) Schiff base complexes as potential tools against SARS-CoV-2 Omicron target proteins: an in silico approach

S Kumar, M Choudhary - New Journal of Chemistry, 2023 - pubs.rsc.org
Herein, we report the in silico design and synthesis of two new nickel (II) coordination
complexes, viz.,[Ni (L1)][(PPh3)] DMF (1) and [Ni (L2)](2), based on Schiff bases derived …

A tris (2-aminoethyl) amine-based zinc complex as a highly water-soluble drug carrier for the anti-COVID-19 drug favipiravir: a joint experimental and theoretical study

F Hajibabaei, SS Movafagh, S Salehzadeh… - Dalton …, 2023 - pubs.rsc.org
Tris (2-aminoethyl) amine (tren) coordinates to a Zn (II) ion to form the [Zn (tren)] 2+ cation
that accepts a monodentate favipiravir (FAV) anion. The results of this work show that the …