The calcium-sensing receptor (CaSR) is a class CG protein–coupled receptor that responds
to multiple endogenous agonists and allosteric modulators, including divalent and trivalent …

As both a sensor of extracellular calcium (Ca2+ o) concentration and a key controller of
Ca2+ o homeostasis, one of the most interesting properties of the calcium-sensing receptor …

The CaSR is a class CG protein-coupled receptor (GPCR) that acts as a multimodal
chemosensor to maintain diverse homeostatic functions. The CaSR is a clinical therapeutic …

Cells meticulously regulate free calcium ion (Ca2+) concentrations, with the endoplasmic
reticulum (ER) being crucial for Ca2+ homeostasis. Disruptions in ER Ca2+ balance can …

The calcium-sensing receptor (CaSR) is a class C G-protein-coupled receptor (GPCR) that
plays a fundamental role in extracellular calcium homeostasis by regulating parathyroid …

The calcium‐sensing receptor is a homodimeric class CG protein‐coupled receptor (GPCR)
that senses extracellular Ca2+ (Ca2+ o) via a dimeric extracellular Venus flytrap (VFT) unit …

Summary Calcium (Ca 2+) is fundamental to organic life, and the ability to detect and
respond to changes in extracellular Ca 2+ ions (Ca 2+ o) is paramount to all living …

UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO Page 1 UNIVERSIDAD NACIONAL
AUTÓNOMA DE MÉXICO PROGRAMA DE ESTUDIOS COMBINADOS EN MEDICINA …

The calcium-sensing receptor (CaSR) is a class CG protein-coupled receptor (GPCR) that
responds to multiple endogenous agonists and allosteric modulators, including di-and tri …

ANOVA analysis of variance ATP adenosine triphosphate AUC area under the curve Ba2+
barium Be2+ beryllium BCT bicarbonate (HCO3-) BSA bovine serum albumin Ca2+ i …