Central nervous system tumors are a significant problem for modern medicine because of
their location. The explanation of the importance of microRNA (miRNA) in the development …

Background Several members of the tripartite motif-containing (TRIM) protein family have
been reported to serve as vital regulators of tumorigenesis. Recent studies have …

Aims Anaplastic ganglioglioma is a rare tumour, and diagnosis has been based on
histological criteria. The 5th edition of the World Health Organization Classification of …

Applications of omics systems biology technologies have enormous promise for radiology
and diagnostics in surgical fields. In this context, the emerging fields of radiomics (a systems …

Pediatric glioblastoma (pGBM) is a lethal cancer with no effective therapies. To understand
the mechanisms of tumor evolution in this cancer, we performed whole-genome sequencing …

MicroRNAs have been found ectopically expressed in many cancers and play essential
roles in tumor EMT progress. Recent studies identified decreased miR-940 expression in …

Marfan syndrome (MFS) and Loeys–Dietz syndrome type 4 (LDS4) are two hereditary
connective tissue disorders. MFS displays ectopia lentis as a distinguishing, characterising …

MicroRNAs (miRNAs) are able to function as either oncogenes or tumor suppressor genes
in tumorigenesis, and have been proposed as novel targets for anticancer treatment. It has …

MicroRNAs (miRNAs/miRs) are a novel class of gene regulators that may be involved in
tumor chemoresistance. Recently, specific miRNA expression profiles have been identified …

Tremendous amount of whole-genome sequencing data have been provided by large
consortium projects such as TCGA (The Cancer Genome Atlas), COSMIC and so on, which …