[HTML][HTML] Diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds

J Sharifi-Rad, CF Rodrigues, F Sharopov… - International journal of …, 2020 - mdpi.com
Heart and blood vessels disorders comprise one of the main causes of death worldwide.
Pharmacologically active natural compounds have been used as a complementary therapy …

[HTML][HTML] Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: A Review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene), a polyphenol found in grapes, red wine,
peanuts, and apples, has been reported to exhibit a wide range of biological and …

[HTML][HTML] Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer

J Lee, JH You, MS Kim, JL Roh - Redox biology, 2020 - Elsevier
Ferroptosis is a newly defined form of cell death induced by iron-dependent accumulation of
lethal lipid peroxidation. Ferroptosis represent a therapeutic strategy to suppress therapy …

[HTML][HTML] COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity

R Miller, AR Wentzel, GA Richards - Medical hypotheses, 2020 - Elsevier
The SARS-CoV-2 hyperinflammatory response is associated with high mortality. This
hypothesis suggests that a deficiency of nicotinamide adenine dinucleotide (NAD+) may be …

[HTML][HTML] Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity

S Verdura, E Cuyàs, E Cortada, J Brunet… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
New strategies to block the immune evasion activity of programmed death ligand-1 (PD-L1)
are urgently needed. When exploring the PD-L1-targeted effects of mechanistically diverse …

Recent advances in health benefits of stilbenoids

YC Koh, CT Ho, MH Pan - Journal of agricultural and food …, 2021 - ACS Publications
Biological targeting or molecular targeting is the main strategy in drug development and
disease prevention. However, the problem of “off-targets” cannot be neglected. Naturally …

[HTML][HTML] Resveratrol's anti-cancer effects through the modulation of tumor glucose metabolism

A Brockmueller, S Sameri, A Liskova, K Zhai… - Cancers, 2021 - mdpi.com
Simple Summary The prevention and treatment of cancer is an ongoing medical challenge.
In the context of personalized medicine, the well-studied polyphenol resveratrol could …

Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review

S Fakhri, SZ Moradi, MH Farzaei, A Bishayee - Seminars in cancer biology, 2022 - Elsevier
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …

[HTML][HTML] Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

Potential therapeutic effects of Resveratrol against SARS-CoV-2.

LH Ramdani, K Bachari - Acta virologica, 2020 - search.ebscohost.com
Abstract Novel Coronavirus COVID-19 or Severe acute respiratory syndrome coronavirus 2
(SARSCoV-2) as well as Severe acute respiratory syndrome coronavirus (SARS-CoV) and …