Dysregulations in energy balance represent a major driver of obesity. Recent evidence
suggests that environmental factors also play a pivotal role in inducing weight gain. Chronic …

Sitting time is associated with increased risks for subclinical atherosclerosis and
cardiovascular disease development, and this is thought to be partially due to sitting …

Background: Chronic kidney disease (CKD) accelerates the development of atherosclerosis,
decreases muscle function, and increases the risk of amputation or death in patients with …

Lower-extremity peripheral arterial disease (PAD) has increased in prevalence, yet
therapeutic development has remained stagnant. Skeletal muscle health and function has …

Chronic kidney disease (CKD) is a strong risk factor for peripheral artery disease (PAD) that
is associated with worsened clinical outcomes. CKD leads to the accumulation of tryptophan …

Objective The present study was undertaken to longitudinally evaluate titers of antibodies
against β2‐glycoprotein I (anti‐β2GPI) and domain 1 (anti‐D1), to identify predictors of …

BACKGROUND: Lower extremity peripheral artery disease (PAD) is a growing epidemic
with limited effective treatment options. Here, we provide a single-nuclei atlas of PAD limb …

Blunted post-occlusive reactive hyperemia (PORH) after prolonged sitting (PS) has been
used as evidence of microvascular dysfunction. However, it has not been determined if …

Advanced Neuromuscular Exercise Physiology, Second Edition, uses a mix of biochemistry,
molecular biology, neurophysiology, and muscle physiology to provide a synthesis of …

Microvascular disease plays a critical role in systemic end-organ dysfunction, and treatment
of microvascular pathologies may greatly reduce cardiovascular morbidity and mortality. The …