Abstract Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with
over 100 known substrates to deal with. How does GSK3 maintain control to selectively …

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified and
studied in the regulation of glycogen synthesis. GSK-3 functions in a wide range of cellular …

Abstract The EGFR/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway plays prominent roles in
malignant transformation, prevention of apoptosis, drug resistance and metastasis. The …

Glycogen synthase kinase 3 (GSK3), a constitutively acting multi‐functional serine threonine
kinase is involved in diverse physiological pathways ranging from metabolism, cell cycle …

Glycogen synthase kinase 3β (GSK3β), a multifunctional serine/threonine kinase found in all
eukaryotes, had been initially identified as a key regulator of insulin-dependent glycogen …

Abstract Glycogen synthase kinase-3 (GSK-3) is associated with various key biological
processes, including glucose regulation, apoptosis, protein synthesis, cell signaling, cellular …

Despite progress in treatment approaches for oral cancer, there has been only modest
improvement in patient outcomes in the past three decades. The frequent treatment failure is …

Abstract Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase is an archetypal
multifunctional moonlighting protein involved in diverse cellular processes including …

The mitochondria are double membrane-bound organelles found in most eukaryotic cells.
They generate most of the cell's energy supply of adenosine triphosphate (ATP). Protein …

As a kinase at the crossroads of numerous metabolic and cell growth signaling pathways,
glycogen synthase kinase-3 beta (GSK-3β) is a highly desirable therapeutic target in cancer …