Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

The intrinsic value of biodiversity extends beyond species diversity, genetic heritage,
ecosystem variability and ecological services, such as climate regulation, water quality …

The current approach of morbidity control of schistosomiasis, a helminth disease of poverty
with considerable public health and socioeconomic impact, is based on preventive …

The development of our society has been based on the use of biodiversity, especially for
medicines and nutrition. Brazil is the nation with the largest biodiversity in the world …

Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …

Drug discovery for schistosomiasis is still limited to a handful of academic laboratories
worldwide, with only a few novel antischistosomal lead compounds being actively …

Artemisinins are a family of sesquiterpene lactones originally derived from the sweet
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …

NuBBEDB is the first library of natural products of Brazilian biodiversity. It includes a large
variety of classes of compounds and structural types of secondary metabolites of plants …

The development of our society has been based on the use of biodiversity, especially for
nutrition, medicines and beauty. Brazil is the nation with the largest biodiversity in the world …