Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Objective: Mild cognitive impairment (MCI) is an important risk state for dementia, particularly
Alzheimer's disease (AD). Depression, anxiety, and apathy are commonly observed …

(1) Background: We proposed to review worldwide estimates of cognitive impairment
prevalence and incidence in adults older than 50 years of age living in the community.(2) …

Introduction Subjective cognitive decline (SCD) manifesting before clinical impairment could
serve as a target population for early intervention trials in Alzheimer's disease (AD). A …

Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …

Background Because anxiety is postulated as a risk factor for dementia, we performed a
systematic review and meta-analysis to investigate whether anxiety predicts cognitive …

Older adults with multiple chronic conditions complicated by other risk factors, such as
deficits in activities of daily living or social barriers, experience multiple challenges in …

Abstract Study Objectives: To examine in cognitively intact older men and women the
associations between subjective sleep quality and 1-yr incident cognitive impairment …

Importance Alzheimer disease (AD) is now known to have a long preclinical phase in which
pathophysiologic processes develop many years, even decades, before the onset of clinical …

Background The increase in average life expectancy increases the risk of illness and frailty
in the elderly, especially in the cognitive arena. This study has the objective to estimate the …