After infection of a cell, the positive-strand RNA genome of Hepatitis C Virus (HCV) directly
serves as the template for translation in the cytosol. By the use of an internal ribosome entry …

Erythrocyte invasion by Plasmodium falciparum merozoites is a highly intricate process in
which Plasmodium falciparum reticulocyte binding-like homologous protein 5 (PfRH5) is an …

Picornaviruses and other positive-strand RNA viruses like hepatitis C virus (HCV) enter the
cell with a single RNA genome that directly serves as the template for translation …

Influenza A remains a significant public health challenge because of the emergence of
antigenically shifted or highly virulent strains,,,,. Antiviral resistance to available drugs such …

Usually proteins are separated by polyacrylamide gel electrophoresis (PAGE) in the
presence of a detergent and under (heat-) denaturing and (non-or) reducing conditions. The …

The Gram-positive bacterium Bacillus subtilis encodes three diadenylate cyclases that
synthesize the essential signaling nucleotide cyclic di-AMP. The activities of the vegetative …

Dyshomeostasis of transition metals iron and copper as well as accumulation of oxidative
DNA damage have been implicated in multitude of human neurodegenerative diseases …

Although immunoassays are the de facto standard for determining subcellular protein
localization in individual cells, antibody probe cross-reactivity and fixation artifacts remain …

The hantavirus envelope glycoproteins Gn and Gc mediate virion assembly and cell entry,
with Gc driving fusion of viral and endosomal membranes. Although the X-ray structures and …

Human serum albumin (HSA) is the most abundant protein in the human body. HSA
injections prepared by fractionating human blood have mainly covered the demand for …