Toll‐like receptor polymorphism in host immune response to infectious diseases: A review
S Mukherjee, S Huda… - Scandinavian journal of …, 2019 - Wiley Online Library
Immunopolymorphism is considered as an important aspect behind the resistance or
susceptibility of the host to an infectious disease. Over the years, researchers have explored …
susceptibility of the host to an infectious disease. Over the years, researchers have explored …
Into the eye of the cytokine storm
JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community
alike, and while the general notion of an excessive or uncontrolled release of …
alike, and while the general notion of an excessive or uncontrolled release of …
Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease
NWJ Schröder, RR Schumann - The Lancet infectious diseases, 2005 - thelancet.com
Toll-like receptors (TLRs) play an important part in the innate immune recognition of
invading microorganisms, initiating sufficient immune responses. Growing amounts of data …
invading microorganisms, initiating sufficient immune responses. Growing amounts of data …
Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics
JL Casanova, L Abel… - Annual review of …, 2011 - annualreviews.org
Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs) have TIR intracellular
domains that engage two main signaling pathways, via the TIR-containing adaptors MyD88 …
domains that engage two main signaling pathways, via the TIR-containing adaptors MyD88 …
Innate immune recognition in infectious and noninfectious diseases of the lung
B Opitz, V van Laak, J Eitel, N Suttorp - American journal of …, 2010 - atsjournals.org
Diseases of the respiratory tract are among the leading causes of death in the world
population. Increasing evidence points to a key role of the innate immune system with its …
population. Increasing evidence points to a key role of the innate immune system with its …
Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation
B Krüger, S Krick, N Dhillon… - Proceedings of the …, 2009 - National Acad Sciences
While studies in animal models have linked Toll-like receptor (TLR) 4 signaling to kidney
injury induced by ischemia and reperfusion, the relevance of TLR4 activation to allograft …
injury induced by ischemia and reperfusion, the relevance of TLR4 activation to allograft …
Bio-aerosols in indoor environment: composition, health effects and analysis
P Srikanth, S Sudharsanam, R Steinberg - Indian journal of medical …, 2008 - Elsevier
Bio-aerosols are airborne particles that are living (bacteria, viruses and fungi) or originate
from living organisms. Their presence in air is the result of dispersal from a site of …
from living organisms. Their presence in air is the result of dispersal from a site of …
Role of Toll-like receptors in the development of sepsis
H Tsujimoto, S Ono, PA Efron, PO Scumpia… - Shock, 2008 - journals.lww.com
The outcome of sepsis and septic shock has not significantly improved in recent decades
despite the development of numerous drugs and supportive care therapies. To reduce …
despite the development of numerous drugs and supportive care therapies. To reduce …
Toll-like receptor polymorphisms and susceptibility to human disease
EA Misch, TR Hawn - Clinical science, 2008 - portlandpress.com
Although several lines of evidence suggest that variation in human inflammation is
genetically controlled, the genes which regulate these responses are largely unknown …
genetically controlled, the genes which regulate these responses are largely unknown …
Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation
D Brooks, LC Barr, S Wiscombe… - European …, 2020 - Eur Respiratory Soc
Inflammation is a key feature in the pathogenesis of sepsis and acute respiratory distress
syndrome (ARDS). Sepsis and ARDS continue to be associated with high mortality. A key …
syndrome (ARDS). Sepsis and ARDS continue to be associated with high mortality. A key …