Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing
According to the latest report from the World Health Organization, an estimated 265,000
deaths still occur every year as a direct result of burn injuries. A widespread range of these …
deaths still occur every year as a direct result of burn injuries. A widespread range of these …
Polyester based polymeric nano and microparticles for pharmaceutical purposes: A review on formulation approaches
The novel polymeric particulate systems show high potential in their clinical effectiveness.
Nevertheless, many of the drug delivery systems developed in the research laboratories …
Nevertheless, many of the drug delivery systems developed in the research laboratories …
Effect of particle size on drug loading and release kinetics of gefitinib-loaded PLGA microspheres
W Chen, A Palazzo, WE Hennink… - Molecular …, 2017 - ACS Publications
Polymeric microspheres have gained widespread application as drug eluting depots.
Typically, drug-loaded polymeric microspheres are prepared by oil-in-water emulsification …
Typically, drug-loaded polymeric microspheres are prepared by oil-in-water emulsification …
Release mechanisms and applications of drug delivery systems for extended-release
Introduction Drug delivery systems with extended-release profiles are ideal in improving
patient compliance with enhanced efficacy. To develop devices capable of a prolonged …
patient compliance with enhanced efficacy. To develop devices capable of a prolonged …
Preparation of sustained release apremilast-loaded PLGA nanoparticles: In vitro characterization and in vivo pharmacokinetic study in rats
Background Apremilast (APM) is a novel, orally administered small molecule drug approved
for treatment of psoriasis or psoriatic arthritis. Due to its low solubility and permeability, it is …
for treatment of psoriasis or psoriatic arthritis. Due to its low solubility and permeability, it is …
Recent progress in drug release testing methods of biopolymeric particulate system
Y Kim, EJ Park, TW Kim, DH Na - Pharmaceutics, 2021 - mdpi.com
Biopolymeric microparticles have been widely used for long-term release formulations of
short half-life chemicals or synthetic peptides. Characterization of the drug release from …
short half-life chemicals or synthetic peptides. Characterization of the drug release from …
Quality by design thinking in the development of long-acting injectable PLGA/PLA-based microspheres for peptide and protein drug delivery
C Zhang, L Yang, F Wan, H Bera, D Cun… - International journal of …, 2020 - Elsevier
Abstract Adopting the Quality by Design (QbD) approach in the drug development process
has transformed from “nice-to-do” into a crucial and required part of the development …
has transformed from “nice-to-do” into a crucial and required part of the development …
Immediate detachment of microneedles by interfacial fracture for sustained delivery of a contraceptive hormone in the skin
Despite their high efficacy and safety, long-acting contraceptive methods are underutilized
among women in some settings because they usually require injection or implantation by …
among women in some settings because they usually require injection or implantation by …
Microemulsion for prolonged release of fenretinide in the mammary tissue and prevention of breast cancer development
The need of pharmacological strategies to preclude breast cancer development motivated
us to develop a non-aqueous microemulsion (ME) capable of forming a depot after …
us to develop a non-aqueous microemulsion (ME) capable of forming a depot after …
Evaluation of β-sitosterol loaded PLGA and PEG-PLA nanoparticles for effective treatment of breast cancer: preparation, physicochemical characterization, and …
β-Sitosterol (β-Sit) is a dietary phytosterol with demonstrated anticancer activity against a
panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic …
panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic …