Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …

High blood pressure is one of the most important risk factors for ischaemic heart disease,
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …

Background Early treatment to prevent severe coronavirus disease 2019 (Covid-19) is an
important component of the comprehensive response to the severe acute respiratory …

Abstract Background Coronavirus disease 2019 (Covid-19) disproportionately results in
hospitalization or death in older patients and those with underlying conditions. Sotrovimab is …

Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …

Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

Obesity and impaired metabolic health are established risk factors for the non-
communicable diseases (NCDs) type 2 diabetes mellitus, cardiovascular disease …

Background Diabetes has been associated with increased COVID-19-related mortality, but
the association between modifiable risk factors, including hyperglycaemia and obesity, and …

Since the initial COVID-19 outbreak in China, much attention has focused on people with
diabetes because of poor prognosis in those with the infection. Initial reports were mainly on …

Background We aimed to ascertain the cumulative risk of fatal or critical care unit-treated
COVID-19 in people with diabetes and compare it with that of people without diabetes, and …