Excessive daytime sleepiness (EDS) is a public health issue. However, it remains largely
undervalued, scarcely diagnosed, and poorly supported. Variations in the definition of EDS …

Funding for the development of this Practice Guidance was provided by the American
Association for the Study of Liver Diseases. MV was supported by aAQ19 Patient-Centered …

The circadian clock comprises a cellular endogenous timing system coordinating the
alignment of physiological processes with geophysical time. Disruption of circadian rhythms …

El desarrollo de la medicina del sueño ha experimentado notables avances por
contribuciones provenientes tanto de las ciencias básicas como de los estudios clínicos …

Sleep medicine is an ambitious cross-disciplinary challenge, requiring the mutual
integration between complementary specialists in order to build a solid framework. Although …

Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐
related quality of life and poor functional status. However, there is limited guidance on …

Non-alcoholic fatty liver disease (NAFLD) is a multisystem disease, which has been
classified as an emerging epidemic not only confined to liver-related morbidity and mortality …

Background Intestinal barrier dysfunction and systemic inflammation are common in
obstructive sleep apnoea (OSA). We aimed to investigate the role of melatonin, an anti …

Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic
cholestatic immune-mediated liver disease characterized by injury to intrahepatic bile ducts …

This narrative review briefly describes the mammalian circadian timing system, the specific
features of the liver clock, also by comparison with other peripheral clocks, the role of the …