DNA methylation: a mechanism for embedding early life experiences in the genome
Although epidemiological data provide evidence that early life experience plays a critical
role in human development, the mechanism of how this works remains in question. Recent …
role in human development, the mechanism of how this works remains in question. Recent …
The social environment and the epigenome
The genome is programmed by the epigenome. Two of the fundamental components of the
epigenome are chromatin structure and covalent modification of the DNA molecule itself by …
epigenome are chromatin structure and covalent modification of the DNA molecule itself by …
Epigenetics, DNA methylation, and chromatin modifying drugs
M Szyf - Annual review of pharmacology and toxicology, 2009 - annualreviews.org
Evidence is emerging that several diseases and behavioral pathologies result from defects
in gene function. The best-studied example is cancer, but other diseases such as …
in gene function. The best-studied example is cancer, but other diseases such as …
The epigenetics of social adversity in early life: implications for mental health outcomes
PO McGowan, M Szyf - Neurobiology of disease, 2010 - Elsevier
An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …
by the epigenome, which is composed predominantly of chromatin and the covalent …
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
C Esau, B Lollo, CF Bennett, SM Freier… - US Patent …, 2010 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
34139820&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
34139820&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
The early life environment and the epigenome
M Szyf - Biochimica et Biophysica Acta (BBA)-General Subjects, 2009 - Elsevier
Several lines of evidence point to the early origin of adult onset disease. A key question is:
what are the mechanisms that mediate the effects of the early environment on our health …
what are the mechanisms that mediate the effects of the early environment on our health …
Computational prediction of miRNAs in Arabidopsis thaliana
A Adai, C Johnson, S Mlotshwa… - Genome …, 2005 - genome.cshlp.org
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in animals and
plants. Comparative genomic computational methods have been developed to predict new …
plants. Comparative genomic computational methods have been developed to predict new …
Epigenetic mechanisms in anti‐cancer actions of bioactive food components–the implications in cancer prevention
B Stefanska, H Karlic, F Varga… - British journal of …, 2012 - Wiley Online Library
The hallmarks of carcinogenesis are aberrations in gene expression and protein function
caused by both genetic and epigenetic modifications. Epigenetics refers to the changes in …
caused by both genetic and epigenetic modifications. Epigenetics refers to the changes in …
Maternal care, the epigenome and phenotypic differences in behavior
The genome is programmed by the epigenome, which is comprised of chromatin and a
covalent modification of DNA by methylation. Epigenetic patterns are sculpted during …
covalent modification of DNA by methylation. Epigenetic patterns are sculpted during …
Diet and the epigenetic (re) programming of phenotypic differences in behavior
Phenotypic diversity is shaped by both genetic and epigenetic mechanisms that program
tissue specific patterns of gene expression. Cells, including neurons, undergo massive …
tissue specific patterns of gene expression. Cells, including neurons, undergo massive …