Sex differences in cardiovascular pathophysiology: why women are overrepresented in heart failure with preserved ejection fraction

AL Beale, P Meyer, TH Marwick, CSP Lam, DM Kaye - Circulation, 2018 - Am Heart Assoc
Consistent epidemiological data demonstrate that patients with heart failure with preserved
ejection fraction (HFpEF) are more likely to be women than men. Exploring mechanisms …

Sex differences in mechanisms of arterial stiffness

JJ DuPont, RM Kenney, AR Patel… - British journal of …, 2019 - Wiley Online Library
Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

Isolated systolic hypertension in young and middle-aged adults and 31-year risk for cardiovascular mortality: the Chicago Heart Association Detection Project in …

Y Yano, J Stamler, DB Garside, ML Daviglus… - Journal of the American …, 2015 - jacc.org
Background: Isolated systolic hypertension (ISH), defined as systolic blood pressure
(SBP)≥ 140 mm Hg and diastolic blood pressure (DBP)< 90 mm Hg, in younger and middle …

Sex differences in arterial stiffness and ventricular-arterial interactions

T Coutinho, BA Borlaug, PA Pellikka, ST Turner… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to assess sex differences in ventricular-arterial interactions.
Background: Heart failure with preserved ejection fraction is more prevalent in women than …

Sex‐specific cardiovascular structure and function in heart failure with preserved ejection fraction

M Gori, CSP Lam, DK Gupta… - European journal of …, 2014 - Wiley Online Library
Aims Women are more likely to develop heart failure with preserved ejection fraction
(HFpEF) than men. We studied the relationship between sex and cardiovascular structure …

Heart failure subtypes and cardiomyopathies in women

EM DeFilippis, A Beale, T Martyn, A Agarwal… - Circulation …, 2022 - Am Heart Assoc
Heart failure affects over 2.6 million women and 3.4 million men in the United States with
known sex differences in epidemiology, management, response to treatment, and outcomes …

Why are women more likely than men to develop heart failure with preserved ejection fraction?

DC Scantlebury, BA Borlaug - Current opinion in cardiology, 2011 - journals.lww.com
The prevalence of HFpEF is increasing and women outnumber men by a 2: 1 ratio. Recent
data have identified striking parallels between structure–function alterations observed in …

Sex differences in heart failure with preserved ejection fraction pathophysiology: a detailed invasive hemodynamic and echocardiographic analysis

AL Beale, S Nanayakkara, L Segan, JA Mariani… - JACC: Heart Failure, 2019 - jacc.org
Objectives: This study sought to identify sex differences in central and peripheral factors that
contribute to the pathophysiology of heart failure with preserved ejection fraction (HFpEF) by …

Arterial stiffness and wave reflection: sex differences and relationship with left ventricular diastolic function

C Russo, Z Jin, V Palmieri, S Homma, T Rundek… - …, 2012 - Am Heart Assoc
Increased arterial stiffness and wave reflection have been reported in heart failure with
normal ejection fraction (HFNEF) and in asymptomatic left ventricular (LV) diastolic …

Gender differences in hypertension: myths and reality

M Doumas, V Papademetriou, C Faselis… - Current hypertension …, 2013 - Springer
Life expectancy is longer in women compared to men, and cardiovascular events occur at a
lower rate and at a later age in females than males. The impact of gender on the prevalence …