Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific
V Guerrini, B Prideaux, L Blanc, N Bruiners… - PLoS …, 2018 - journals.plos.org
Foam cells are lipid-laden macrophages that contribute to the inflammation and tissue
damage associated with many chronic inflammatory disorders. Although foam cell …
damage associated with many chronic inflammatory disorders. Although foam cell …
Molecular and microbiological methods for the identification of nonreplicating Mycobacterium tuberculosis
JP Sarathy - PLoS pathogens, 2024 - journals.plos.org
Chronic tuberculosis (TB) disease, which requires months-long chemotherapy with multiple
antibiotics, is defined by diverse pathological manifestations and bacterial phenotypes …
antibiotics, is defined by diverse pathological manifestations and bacterial phenotypes …
Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) remains a grave threat to world health with emerging drug
resistant strains. One prominent feature of Mtb infection is the extensive reprogramming of …
resistant strains. One prominent feature of Mtb infection is the extensive reprogramming of …
[HTML][HTML] The inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach
FO Cope, B Abbruzzese, J Sanders, W Metz… - Nuclear medicine and …, 2016 - Elsevier
In considering the challenges of approaches to clinical imaging, we are faced with choices
that sometimes are impacted by rather dogmatic notions about what is a better or worse …
that sometimes are impacted by rather dogmatic notions about what is a better or worse …
MUSASHI-mediated expression of JMJD3, a H3K27me3 demethylase, is involved in foamy macrophage generation during mycobacterial infection
Foamy macrophages (FM) s harbor lipid bodies that not only assist mycobacterial
persistence within the granulomas but also are sites for intracellular signaling and …
persistence within the granulomas but also are sites for intracellular signaling and …
Nutritional status positively impacts humoral immunity against its Mycobacterium tuberculosis, disease progression, and vaccine development
M Niki, T Yoshiyama, H Nagai, Y Miyamoto, M Niki… - PloS one, 2020 - journals.plos.org
Nutritional status contributes to the regulation of immune responses against pathogens, and
malnutrition has been considered as a risk factor for tuberculosis (TB). Mycobacterium …
malnutrition has been considered as a risk factor for tuberculosis (TB). Mycobacterium …
In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice
Despite considerable progress in understanding the pathogenesis of Mycobacterium
tuberculosis (Mtb), development of new therapeutics and vaccines against it has proven …
tuberculosis (Mtb), development of new therapeutics and vaccines against it has proven …
Exploiting Reporter Mycobacterium tuberculosis Strains to Illuminate Infection Heterogeneity in vivo and Identify New Antitubercular Compounds
RC Lavin - 2023 - search.proquest.com
Tuberculosis disease, cause by Mycobacterium tuberculosis (Mtb), continues to be a global
health threat and is the leading cause of death by a bacterial infection worldwide …
health threat and is the leading cause of death by a bacterial infection worldwide …