Plant growth regulation in cell and tissue culture in vitro

TP Pasternak, D Steinmacher - Plants, 2024 - mdpi.com
Precise knowledge of all aspects controlling plant tissue culture and in vitro plant
regeneration is crucial for plant biotechnologists and their correlated industry, as there is …

[HTML][HTML] Artificial intelligence and machine learning applications for cultured meat

ME Todhunter, S Jubair, R Verma, R Saqe… - Frontiers in Artificial …, 2024 - frontiersin.org
Cultured meat has the potential to provide a complementary meat industry with reduced
environmental, ethical, and health impacts. However, major technological challenges …

Recent advances in culture medium design for enhanced production of monoclonal antibodies in CHO cells: A comparative study of machine learning and systems …

H Kavoni, ISP Savizi, NE Lewis… - Biotechnology Advances, 2024 - Elsevier
The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells
has revolutionized the treatment of numerous diseases, solidifying their position as a …

Identifying optimal substrate classes of membrane transporters

A Denger, V Helms - PloS one, 2024 - journals.plos.org
Membrane transporters are responsible for moving a wide variety of molecules across
biological membranes, making them integral to key biological pathways in all organisms …

Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute

N Gangwar, K Balraj, AS Rathore - Applied Microbiology and …, 2024 - Springer
Cell culture media play a critical role in cell growth and propagation by providing a
substrate; media components can also modulate the critical quality attributes (CQAs) …

Neural network-ant-colony hybrid optimization of a bacterial fruit juice clarifying metallo-neutral-protease production

E Ikharia, M Ekpenyong, D Ubi, E Akwagiobe… - Journal of Food Science …, 2024 - Springer
Neutral proteases are invaluable for food, pharmaceutical, and feed industries because of
their mild catalysis. This study reports the production and potential food industry application …

Statistical versus neural network-embedded swarm intelligence optimization of a metallo-neutral-protease production: activity kinetics and food industry applications

MG Ekpenyong, SP Antai - Preparative Biochemistry & …, 2024 - Taylor & Francis
An integrated approach involving response surface methodology (RSM) and artificial neural
network-ant-colony hybrid optimization (ANN-ACO) was adopted to develop a bioprocess …

Machine Learning Approaches to 3D Models for Drug Screening

VA da Silva, R Sharma, E Shteinberg, V Patel… - Biomedical Materials & …, 2024 - Springer
The creation of precise, functional 3D tissues can enable effective drug screening as well as
advancements in regenerative medicine. However, the inherent limitations present during …

Optimization of an Alternative Culture Medium for Phycocyanin Production from Arthrospira platensis under Laboratory Conditions

DA Freire Balseca, KS Castro Reyes… - Microorganisms, 2024 - mdpi.com
Arthrospira platensis, known as spirulina, is a cyanobacterium with multiple nutritional
benefits, as it contains substantial amounts of proteins, fatty acids, and pigments. However …

Accelerating Cell Culture Media Development Using Bayesian Optimization-Based Iterative Experimental Design

H Narayanan, J Hinckley, R Barry, B Dang, LA Wolffe… - bioRxiv, 2024 - biorxiv.org
Optimizing operational conditions for complex biological systems used in life sciences
research and biotechnology is an arduous task. Here, we have applied a Bayesian …