Challenges of big data analysis

J Fan, F Han, H Liu - National science review, 2014 - academic.oup.com
Big Data bring new opportunities to modern society and challenges to data scientists. On the
one hand, Big Data hold great promises for discovering subtle population patterns and …

Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging

X Bai, M Vestal, R Berman, M Negishi… - Journal of …, 2010 - Soc Neuroscience
Absence seizures are 5–10 s episodes of impaired consciousness accompanied by 3–4 Hz
generalized spike-and-wave discharge on electroencephalography (EEG). The time course …

Large-scale hypothesis testing for causal mediation effects with applications in genome-wide epigenetic studies

Z Liu, J Shen, R Barfield, J Schwartz… - Journal of the …, 2022 - Taylor & Francis
In genome-wide epigenetic studies, it is of great scientific interest to assess whether the
effect of an exposure on a clinical outcome is mediated through DNA methylations …

A group model for stable multi-subject ICA on fMRI datasets

G Varoquaux, S Sadaghiani, P Pinel, A Kleinschmidt… - Neuroimage, 2010 - Elsevier
Spatial Independent Component Analysis (ICA) is an increasingly used data-driven method
to analyze functional Magnetic Resonance Imaging (fMRI) data. To date, it has been used to …

Simultaneous EEG, fMRI, and behavior in typical childhood absence seizures

R Berman, M Negishi, M Vestal, M Spann… - …, 2010 - Wiley Online Library
Purpose: Absence seizures cause transient impairment of consciousness. Typical absence
seizures occur in children, and are accompanied by 3–4‐Hz spike–wave discharges …

The effect of correlation in false discovery rate estimation

A Schwartzman, X Lin - Biometrika, 2011 - academic.oup.com
The objective of this paper is to quantify the effect of correlation in false discovery rate
analysis. Specifically, we derive approximations for the mean, variance, distribution and …

Association between tumor location and neurocognitive functioning using tumor localization maps

EJJ Habets, EJ Hendriks, MJB Taphoorn… - Journal of neuro …, 2019 - Springer
Introduction Patients with diffuse glioma often experience neurocognitive impairment
already prior to surgery. Pertinent information on whether damage to a specific brain region …

Resection probability maps for quality assessment of glioma surgery without brain location bias

PC De Witt Hamer, EJ Hendriks, E Mandonnet… - PloS one, 2013 - journals.plos.org
Background Intraoperative brain stimulation mapping reduces permanent postoperative
deficits and extends tumor removal in resective surgery for glioma patients. Successful …

Linking late cognitive outcome with glioma surgery location using resection cavity maps

EJ Hendriks, EJJ Habets, MJB Taphoorn… - Human brain …, 2018 - Wiley Online Library
Patients with a diffuse glioma may experience cognitive decline or improvement upon
resective surgery. To examine the impact of glioma location, cognitive alteration after glioma …

The joint effect of aging and HIV infection on microstructure of white matter bundles

T Kuhn, Y Jin, C Huang, Y Kim, TM Nir… - Human brain …, 2019 - Wiley Online Library
Recent evidence suggests the aging process is accelerated by HIV. Degradation of white
matter (WM) has been independently associated with HIV and healthy aging. Thus, WM may …