[HTML][HTML] Focus: Death: Organ dysfunction in sepsis: An ominous trajectory from infection to death
C Caraballo, F Jaimes - The Yale journal of biology and medicine, 2019 - ncbi.nlm.nih.gov
Sepsis is a highly complex and lethal syndrome with highly heterogeneous clinical
manifestations that makes it difficult to detect and treat. It is also one of the major and most …
manifestations that makes it difficult to detect and treat. It is also one of the major and most …
Acute kidney injury
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
Extracellular DNA traps in inflammation, injury and healing
C Daniel, M Leppkes, LE Muñoz, G Schley… - Nature Reviews …, 2019 - nature.com
Following strong activation signals, several types of immune cells reportedly release
chromatin and granular proteins into the extracellular space, forming DNA traps. This …
chromatin and granular proteins into the extracellular space, forming DNA traps. This …
[HTML][HTML] Role of perioperative hypotension in postoperative acute kidney injury: a narrative review
Perioperative hypotension is common and associated with poor outcomes, including acute
kidney injury (AKI). The mechanistic link between perioperative hypotension and AKI is at …
kidney injury (AKI). The mechanistic link between perioperative hypotension and AKI is at …
Targeting oxidative stress in septic acute kidney injury: from theory to practice
Sepsis is the leading cause of acute kidney injury (AKI) and leads to increased morbidity
and mortality in intensive care units. Current treatments for septic AKI are largely supportive …
and mortality in intensive care units. Current treatments for septic AKI are largely supportive …
[HTML][HTML] Non-coding RNAs in kidney injury and repair
Z Liu, Y Wang, S Shu, J Cai… - American Journal of …, 2019 - journals.physiology.org
Acute kidney injury (AKI) is a major kidney disease featured by a rapid decline of renal
function. Pathologically, AKI is characterized by tubular epithelial cell injury and death …
function. Pathologically, AKI is characterized by tubular epithelial cell injury and death …
Inhibition of the NADPH oxidase pathway reduces ferroptosis during septic renal injury in diabetic mice
W Yao, H Liao, M Pang, L Pan, Y Guan… - Oxidative medicine …, 2022 - Wiley Online Library
Background. Obesity and type 2 diabetes mellitus (DM) contribute to a higher mortality rate
in patients with septic acute kidney injury (AKI) during sepsis. Reactive oxygen species …
in patients with septic acute kidney injury (AKI) during sepsis. Reactive oxygen species …
The pathophysiology of sepsis-associated AKI
S Kuwabara, E Goggins, MD Okusa - Clinical Journal of the …, 2022 - journals.lww.com
Sepsis-associated AKI is a life-threatening complication that is associated with high
morbidity and mortality in patients who are critically ill. Although it is clear early supportive …
morbidity and mortality in patients who are critically ill. Although it is clear early supportive …
Reversal of the pathophysiological responses to gram-negative sepsis by megadose vitamin C
YR Lankadeva, RM Peiris, N Okazaki… - Critical care …, 2021 - journals.lww.com
Objectives: Oxidative stress appears to initiate organ failure in sepsis, justifying treatment
with antioxidants such as vitamin C at megadoses. We have therefore investigated the safety …
with antioxidants such as vitamin C at megadoses. We have therefore investigated the safety …
[PDF][PDF] 肝素结合蛋白联合白介素-6 对持续性脓毒症急性肾损伤的预测价值
金仁华, 李静, 沈骁, 孙加奎, 穆心苇 - 临床急诊杂志, 2023 - lcjzen.whuhzzs.com
肝素结合蛋白联合白介素-6对持续性脓毒症急性肾损伤的预测价值 Page 1 2023年 临床急诊
杂志 24卷3期 JournalofClinicalEmergency(China) 引用本文:金仁华,李静,沈骁,等.肝素结合 …
杂志 24卷3期 JournalofClinicalEmergency(China) 引用本文:金仁华,李静,沈骁,等.肝素结合 …