Asian Americans (AsA), Native Hawaiians, and Pacific Islanders (NHPI) comprise 7.7% of
the US population, and AsA have had the fastest growth rate since 2010. Yet the National …

Current American Thoracic Society (ATS) standards promote the use of race and ethnicity-
specific reference equations for pulmonary function test (PFT) interpretation. There is rising …

Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …

Pulmonary function testing is often considered the basis for diagnosis in many categories of
pulmonary disease. Although most of the testing methodologies are well established and …

Background Inhaled corticosteroids have been used in patients with chronic obstructive
pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not …

Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality
worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed …

Background Chronic obstructive pulmonary disease (COPD) often coexists with
cardiovascular disease. Treatments for airflow limitation might improve survival and both …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide.
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

Rationale: Normal values for FEV1 and FVC are currently calculated using cross-sectional
reference equations that include terms for race/ethnicity, an approach that may reinforce …

Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) is a multicentre
observational study of chronic obstructive pulmonary disease (COPD) designed to guide …