The Circulating Proteome─ Technological Developments, Current Challenges, and Future Trends
Recent improvements in proteomics technologies have fundamentally altered our capacities
to characterize human biology. There is an ever-growing interest in using these novel …
to characterize human biology. There is an ever-growing interest in using these novel …
timsTOF HT improves protein identification and quantitative reproducibility for deep unbiased plasma protein biomarker discovery
D Vitko, WF Chou, S Nouri Golmaei… - Journal of Proteome …, 2024 - ACS Publications
Mass spectrometry (MS) is a valuable tool for plasma proteome profiling and disease
biomarker discovery. However, wide-ranging plasma protein concentrations, along with …
biomarker discovery. However, wide-ranging plasma protein concentrations, along with …
Deep profiling of plasma proteoforms with engineered nanoparticles for top-down proteomics
The dynamic range challenge for the detection of proteins and their proteoforms in human
plasma has been well documented. Here, we use the nanoparticle protein corona approach …
plasma has been well documented. Here, we use the nanoparticle protein corona approach …