Role of the microbiota in response to and recovery from cancer therapy

SJ Blake, Y Wolf, B Boursi, DJ Lynn - Nature Reviews Immunology, 2024 - nature.com
Our understanding of how the microbiota affects the balance between response to and
failure of cancer treatment by modulating the tumour microenvironment and systemic …

Nutritional modulation of the gut microbiome in allogeneic hematopoietic stem cell transplantation recipients

E Muratore, D Leardini, F Baccelli, F Venturelli… - Frontiers in …, 2022 - frontiersin.org
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents a potentially
curative strategy for many oncological and non-oncological diseases, but it is associated …

Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation

JC Swarte, Y Li, S Hu, JR Björk, R Gacesa… - Science Translational …, 2022 - science.org
Organ transplantation is a life-saving treatment for patients with end-stage disease, but
survival rates after transplantation vary considerably. There is now increasing evidence that …

Allogeneic hematopoietic cell transplantation, the microbiome, and graft-versus-host disease

YF van Lier, J Vos, B Blom, MD Hazenberg - Gut Microbes, 2023 - Taylor & Francis
Many patients with hematological malignancies, such as acute myeloid leukemia, receive an
allogeneic hematopoietic cell transplantation (HCT) to cure their underlying condition …

[HTML][HTML] Multifaceted effects of obesity on cancer immunotherapies: bridging preclinical models and clinical data

LV Vick, RJ Canter, AM Monjazeb… - Seminars in cancer biology, 2023 - Elsevier
Obesity, defined by excessive body fat, is a highly complex condition affecting numerous
physiological processes, such as metabolism, proliferation, and cellular homeostasis. These …

Translating MSC therapy in the age of obesity

L Boland, LM Bitterlich, AE Hogan, JA Ankrum… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option
to treat a number of inflammatory conditions including COVID-19 acute respiratory distress …

Emerging roles of the gut microbiota in cancer immunotherapy

Z Shi, H Li, W Song, Z Zhou, Z Li, M Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Gut microbiota represents a hidden treasure vault encompassing trillions of microorganisms
that inhabit the intestinal epithelial barrier of the host. In the past decade, numerous in-vitro …

The emerging role of nutritional support in the supportive care of pediatric patients undergoing hematopoietic stem cell transplantation

E Muratore, D Leardini, F Baccelli, F Venturelli… - Frontiers in …, 2023 - frontiersin.org
Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) represents a potentially
curative strategy for many oncological, hematological, metabolic, and immunological …

Chronic GvHD NIH consensus project biology task force: Evolving path to personalized treatment of chronic GvHD

NP Buxbaum, G Socié, GR Hill… - Blood …, 2023 - ashpublications.org
Chronic graft-versus-host disease (cGvHD) remains a prominent barrier to allogeneic
hematopoietic stem cell transplantion as the leading cause of nonrelapse mortality and …

Altered intestinal microbiome and epithelial damage aggravate intestinal graft-versus-host disease

F Gao, H Wu, L Wang, Y Zhao, H Huang - Gut Microbes, 2023 - Taylor & Francis
Despite significant achievements in hematopoietic stem cell transplantation (HSCT), graft-
versus-host disease (GVHD), especially intestinal GVHD, remains a major obstacle to this …