Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules
AD Bondarev, MM Attwood, J Jonsson… - Frontiers in …, 2022 - frontiersin.org
The phosphodiesterase (PDE) enzymes, key regulator of the cyclic nucleotide signal
transduction system, are long-established as attractive therapeutic targets. During …
transduction system, are long-established as attractive therapeutic targets. During …
The management of erectile dysfunction in men with diabetes mellitus unresponsive to phosphodiesterase type 5 inhibitors
AA Cayetano‐Alcaraz, T Tharakan, R Chen… - …, 2023 - Wiley Online Library
Introduction Erectile dysfunction is associated with diabetes mellitus with an estimated
prevalence of 52.5% in the diabetic population. The first‐line therapy for erectile dysfunction …
prevalence of 52.5% in the diabetic population. The first‐line therapy for erectile dysfunction …
[HTML][HTML] The effect of phosphodiesterase-type 5 inhibitors on erectile function: an overview of systematic reviews
N Pyrgidis, I Mykoniatis, AB Haidich, M Tirta… - Frontiers in …, 2021 - frontiersin.org
Background: Multiple systematic reviews explore the effect of phosphodiesterase type 5
(PDE5) inhibitors on erectile dysfunction (ED), with each study addressing specific …
(PDE5) inhibitors on erectile dysfunction (ED), with each study addressing specific …
The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of …
Purpose Erectile dysfunction (ED) is one of the most prevalent male sexual dysfunctions. ED
has been in the past mistakenly considered a purely psycho-sexological symptom by …
has been in the past mistakenly considered a purely psycho-sexological symptom by …
The effect of low-intensity shock wave therapy on moderate erectile dysfunction: a double-blind, randomized, sham-controlled clinical trial
D Kalyvianakis, I Mykoniatis, N Pyrgidis… - Journal of …, 2022 - journals.lww.com
Purpose: We conducted the first double-blind, randomized, sham-controlled trial evaluating
the efficacy and safety of low-intensity shock wave therapy (LiST) exclusively in patients with …
the efficacy and safety of low-intensity shock wave therapy (LiST) exclusively in patients with …
Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
GC Petre, F Francini-Pesenti, A Vitagliano, G Grande… - Nutrients, 2023 - mdpi.com
The use of nutraceutical products to enhance male sexual performance has a long history,
especially with regard to the treatment of erectile dysfunction (ED). Alternative treatments for …
especially with regard to the treatment of erectile dysfunction (ED). Alternative treatments for …
New frontiers of extracorporeal shock wave medicine in urology from bench to clinical studies
PY Chen, JH Cheng, ZS Wu, YC Chuang - Biomedicines, 2022 - mdpi.com
A shock wave (SW), which carries energy and propagates through a medium, is a type of
continuous transmitted sonic wave that can achieve rapid energy transformations. SWs have …
continuous transmitted sonic wave that can achieve rapid energy transformations. SWs have …
Platelet-rich plasma for the treatment of erectile dysfunction: a systematic review of preclinical and clinical studies
E Poulios, I Mykoniatis, N Pyrgidis… - Sexual Medicine …, 2023 - academic.oup.com
Introduction There has been tremendous growth in regenerative medicine during the last
decade. For erectile dysfunction (ED), after the inclusion of low-intensity shockwave therapy …
decade. For erectile dysfunction (ED), after the inclusion of low-intensity shockwave therapy …
Assessment of conservative combination therapies for active and stable Peyronie's disease: a systematic review and meta-analysis
Abstract Context In patients with Peyronie's disease (PD), oral, injected, or topical agents
provide limited efficacy. In this setting, combination of two or more conservative treatments …
provide limited efficacy. In this setting, combination of two or more conservative treatments …
Prostaglandins as a topical therapy for erectile dysfunction: a comprehensive review
M Hamzehnejadi, MR Tavakoli… - Sexual medicine …, 2022 - academic.oup.com
Introduction Erectile dysfunction (ED) is a substantial cause of dissatisfaction among many
men. This discontentment has led to the emergence of various drug treatment options for this …
men. This discontentment has led to the emergence of various drug treatment options for this …