Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ

Y Cao, X Zhang, W Shang, J Xu, X Wang, X Hu, Y Ao… - PLoS …, 2013 - journals.plos.org
Objective Mitochondria play important roles in many types of cells. However, little is known
about mitochondrial function in chondrocytes. This study was undertaken to explore possible …

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin–NFATc3–Etv2 pathway

YJ Wang, J Huang, W Liu, X Kou, H Tang… - Journal of molecular …, 2017 - academic.oup.com
Abstracts Ca2+ signals participate in various cellular processes with spatial and temporal
dynamics, among which, inositol 1, 4, 5-trisphosphate receptors (IP3Rs)-mediated Ca2+ …

Functional expression of the Ca2+ signaling machinery in human embryonic stem cells

JJ Huang, YJ Wang, M Zhang, P Zhang… - Acta Pharmacologica …, 2017 - nature.com
Emerging evidence suggests that Ca 2+ signals are important for the self-renewal and
differentiation of human embryonic stem cells (hESCs). However, little is known about the …

Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations

CS Jian, TT Hou, RK Yin, HP Cheng… - Science China Life …, 2014 - Springer
The mitochondria play essential roles in both intracellular calcium and reactive oxygen
species signaling. As a newly discovered universal and fundamental mitochondrial …

Coupling switch of P2Y-IP3 receptors mediates differential Ca2+ signaling in human embryonic stem cells and derived cardiovascular progenitor cells

J Huang, M Zhang, P Zhang, H Liang, K Ouyang… - Purinergic …, 2016 - Springer
Purinergic signaling mediated by P2 receptors (P2Rs) plays important roles in embryonic
and stem cell development. However, how it mediates Ca 2+ signals in human embryonic …

[引用][C] 线粒体稳定高钙信号诱发超氧炫

简崇书, 侯婷婷, 殷荣康, 程和平, 王显花 - 中国科学: 生命科学, 2013