Virulence factors of the Mycobacterium tuberculosis complex
MA Forrellad, LI Klepp, A Gioffré, J Sabio y Garcia… - Virulence, 2013 - Taylor & Francis
The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
Borrelia burgdorferi Keeps Moving and Carries on: A Review of Borrelial Dissemination and Invasion
JA Hyde - Frontiers in immunology, 2017 - frontiersin.org
Borrelia burgdorferi is the etiological agent of Lyme disease, a multisystemic, multistage,
inflammatory infection resulting in patients experiencing cardiac, neurological, and arthritic …
inflammatory infection resulting in patients experiencing cardiac, neurological, and arthritic …
HtrA protease family as therapeutic targets
J Skorko-Glonek, D Zurawa-Janicka… - Current …, 2013 - ingentaconnect.com
The HtrA proteases degrade damaged proteins and thus control the quality of proteins and
protect cells against the consequences of various stresses; they also recognize specific …
protect cells against the consequences of various stresses; they also recognize specific …
Engineering of serine protease for improved thermostability and catalytic activity using rational design
NM Ashraf, A Krishnagopal, A Hussain… - International journal of …, 2019 - Elsevier
The study involves the isolation and characterization of a serine peptidase, named SP, from
Pseudomonas aeruginosa. In addition to basic characterization, the protein was engineered …
Pseudomonas aeruginosa. In addition to basic characterization, the protein was engineered …
Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response
G Hansen, R Hilgenfeld - Cellular and Molecular Life Sciences, 2013 - Springer
Protein quality control is vital for all living cells and sophisticated molecular mechanisms
have evolved to prevent the excessive accumulation of unfolded proteins. High-temperature …
have evolved to prevent the excessive accumulation of unfolded proteins. High-temperature …
Tea polyphenol liposomes overcome gastric mucus to treat helicobacter pylori infection and enhance the intestinal microenvironment
Infection with Helicobacter pylori (Hp) is one of the leading causes of stomach cancer. The
ability to treat Hp infection is hampered by a lack of stomach gastric acid environment. This …
ability to treat Hp infection is hampered by a lack of stomach gastric acid environment. This …
Structural insights into the activation mechanisms of human HtrA serine proteases
D Zurawa-Janicka, T Wenta, M Jarzab… - Archives of biochemistry …, 2017 - Elsevier
Human HtrA1-4 proteins belong to the HtrA family of evolutionarily conserved serine
proteases and function as important modulators of many physiological processes, including …
proteases and function as important modulators of many physiological processes, including …
Heterozygous mutations of HTRA1 gene in patients with familial cerebral small vessel disease
I Di Donato, S Bianchi, GN Gallus… - CNS neuroscience & …, 2017 - Wiley Online Library
Aims Cerebral small vessel disease (SVD) is the leading cause of vascular dementia.
Although the most of cases are sporadic, familial monogenic causes have been identified in …
Although the most of cases are sporadic, familial monogenic causes have been identified in …
Processing of D1 protein: a mysterious process carried out in thylakoid lumen
N Inagaki - International Journal of Molecular Sciences, 2022 - mdpi.com
In oxygenic photosynthetic organisms, D1 protein, a core subunit of photosystem II (PSII),
displays a rapid turnover in the light, in which D1 proteins are distinctively damaged and …
displays a rapid turnover in the light, in which D1 proteins are distinctively damaged and …
Function of serine protease HtrA in the lifecycle of the foodborne pathogen Campylobacter jejuni
M Boehm, D Simson, U Escher, AM Schmidt… - European Journal of …, 2018 - akjournals.com
Campylobacter jejuni is a major food-borne zoonotic pathogen, responsible for a large
proportion of bacterial gastroenteritis cases, as well as Guillian-Barré and Miller-Fisher …
proportion of bacterial gastroenteritis cases, as well as Guillian-Barré and Miller-Fisher …