This study describes the occurrence of renal failure among 1353 newly diagnosed cases of
multiple myeloma. Renal function was evaluated by serum creatinine concentration in 1353 …

Gap junctions are intercellular channels that link the cytoplasm of neighboring cells in
animals, enabling straight passage of ions and small molecules. Two different protein …

We describe predictions made using the Rosetta structure prediction methodology for the
Eighth Critical Assessment of Techniques for Protein Structure Prediction. Aggressive …

It is widely assumed that new proteins are created by duplication, fusion, or fission of
existing coding sequences. Another mechanism of protein birth is provided by overlapping …

Background The Vibrio parahaemolyticus type III secreted effector VopS contains a fic
domain that covalently modifies Rho GTPase threonine with AMP to inhibit downstream …

Protein modeling has been a very challenging problem in drug discovery and computational
biology. The latest advances and progress in computational power have helped to solve this …

Abstract Background Argonaute (Ago) proteins interact with small regulatory RNAs to
mediate gene regulatory pathways. A recent report by Kiriakidou et al.[1] describes an MC …

Motivation: A recent development in sequence-based remote homologue detection is the
introduction of profile–profile comparison methods. These are more powerful than previous …

Background Machine learning-based methods have been proven to be powerful in
developing new fold recognition tools. In our previous work [Zhang, Kochhar and Grigorov …

Homology modeling is based on the observation that related protein sequences adopt
similar three-dimensional structures. Hence, a homology model of a protein can be derived …