Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies

A Nemmar, JA Holme, I Rosas… - BioMed research …, 2013 - Wiley Online Library
Epidemiological and clinical studies have linked exposure to particulate matter (PM) to
adverse health effects, which may be registered as increased mortality and morbidity from …

Mitochondrial dysfunction as a hallmark of environmental injury

C Duarte-Hospital, A Tête, F Brial, L Benoit, M Koual… - Cells, 2021 - mdpi.com
Environmental factors including diet, sedentary lifestyle and exposure to pollutants largely
influence human health throughout life. Cellular and molecular events triggered by an …

Wavefunction and reactivity study of benzo [a] pyrene diol epoxide and its enantiomeric forms

T Lu, S Manzetti - Structural Chemistry, 2014 - Springer
Benzo [a] pyrene is a known carcinogen, which derives from fossil fuel combustion, cigarette
smoke, and generic biomass combustion including traffic emissions. This potent carcinogen …

Hippophae rhamnoides polysaccharides protect IPEC-J2 cells from LPS-induced inflammation, apoptosis and barrier dysfunction in vitro via inhibiting TLR4/NF-κB …

L Zhao, M Li, K Sun, S Su, T Geng, H Sun - International Journal of …, 2020 - Elsevier
Inflammatory response caused by early weaning stress in piglets is associated with various
diseases. The Hippophae rhamnoides polysaccharide (HRP) exhibits anti-inflammatory …

Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells

C Bouaziz, E El Golli, S Abid-Essefi, C Brenner… - Toxicology, 2008 - Elsevier
Mycotoxins, secondary metabolites produced by moulds, have been shown to cause diverse
toxic effects in animals and are also suspected of disease causation in humans. The present …

Metabolic activation of benzo[ a ]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo …

VM Arlt, M Stiborova, CJ Henderson… - …, 2008 - academic.oup.com
Many studies using mammalian cellular and subcellular systems have demonstrated that
polycyclic aromatic hydrocarbons, including benzo [a] pyrene (BaP), are metabolically …

Benzo [a] pyrene induces autophagic and pyroptotic death simultaneously in HL-7702 human normal liver cells

L Yuan, J Liu, H Deng, C Gao - Journal of agricultural and food …, 2017 - ACS Publications
As a common polycyclic aromatic hydrocarbon compound, benzo [a] pyrene (BaP) is readily
produced in processing of oil and fatty foods. It is not only a strong carcinogen but also a …

The environmental carcinogen benzo [a] pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival

K Hardonnière, E Saunier, A Lemarié, M Fernier… - Scientific reports, 2016 - nature.com
Cancer cells display alterations in many cellular processes. One core hallmark of cancer is
the Warburg effect which is a glycolytic reprogramming that allows cells to survive and …

Component Analysis and Anti-Colorectal Cancer Mechanism via AKT/mTOR Signalling Pathway of Sanghuangporus vaninii Extracts

S Guo, W Duan, Y Wang, L Chen, C Yang, X Gu, Q Xue… - Molecules, 2022 - mdpi.com
Sanghuangporus vaninii (Ljub.) LW Zhou & YC Dai (SV) is a major cultivar of Sanghuang,
which is well known as an excellent anti-tumour drug and reaches the mainstream market in …

TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B [a] P in vivo

X Ling, W Yang, P Zou, G Zhang, Z Wang, X Zhang… - Environmental …, 2018 - Elsevier
Increasing evidence shows that impaired telomere function is associated with male infertility,
and various environmental factors are believed to play a pivotal role in telomerase …