Artificial intelligence to deep learning: machine intelligence approach for drug discovery
Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time …
companies and chemical scientists. However, low efficacy, off-target delivery, time …
Machine learning for synergistic network pharmacology: a comprehensive overview
Network pharmacology is an emerging area of systematic drug research that attempts to
understand drug actions and interactions with multiple targets. Network pharmacology has …
understand drug actions and interactions with multiple targets. Network pharmacology has …
Recent advances of chroman-4-one derivatives: synthetic approaches and bioactivities
S Emami, Z Ghanbarimasir - European Journal of Medicinal Chemistry, 2015 - Elsevier
Chroman-4-one scaffold is a privileged structure in heterocyclic chemistry and drug
discovery. Also, chroman-4-ones are important intermediates and interesting building blocks …
discovery. Also, chroman-4-ones are important intermediates and interesting building blocks …
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy
The azole antifungal drugs are an important class of chemotherapeutic agents with broad-
spectrum of activity against yeasts and filamentous fungi, act in the ergosterol biosynthetic …
spectrum of activity against yeasts and filamentous fungi, act in the ergosterol biosynthetic …
Chromanone-A prerogative therapeutic scaffold: an overview
S Kamboj, R Singh - Arabian journal for science and engineering, 2022 - Springer
Chromanone or Chroman-4-one is the most important and interesting heterobicyclic
compound and acts as a building block in medicinal chemistry for isolation, designing and …
compound and acts as a building block in medicinal chemistry for isolation, designing and …
Therapeutic use of Guggulsterone in COVID-19 induced obesity (COVIBESITY) and significant role in immunomodulatory effect
L Preethi, N Ganamurali, D Dhanasekaran… - Obesity Medicine, 2021 - Elsevier
COVID-19 has emerged as a major cause of health crisis around the world. Psychosocial,
Behavioral and metabolic changes especially weight gain, among variety of population was …
Behavioral and metabolic changes especially weight gain, among variety of population was …
[HTML][HTML] In silico and pharmacokinetic assessment of echinocystic acid effectiveness in Alzheimer's disease like pathology
A Singh, C Vellapandian - Future Science OA, 2024 - ncbi.nlm.nih.gov
Aim: Alzheimer's disease causes dementia which impairs the cognitive domains.
Methodology: The pharmacokinetic characteristics and biological activity of echinocystic …
Methodology: The pharmacokinetic characteristics and biological activity of echinocystic …
Immunoinformatics and Molecular Docking Studies Predicted Potential Multiepitope‐Based Peptide Vaccine and Novel Compounds against Novel SARS‐CoV‐2 …
Background. Coronaviruses (CoVs) are enveloped positive‐strand RNA viruses which have
club‐like spikes at the surface with a unique replication process. Coronaviruses are …
club‐like spikes at the surface with a unique replication process. Coronaviruses are …
Synthesis and In Vitro Studies for Structure-Based Design of Novel Chalcones As Antitubercular Agents Targeting InhA
Background: The authors aimed to estimate the therapeutic potential of novel chalcones
against tuberculosis. Methods: 11 synthesized compounds were tested for in vitro …
against tuberculosis. Methods: 11 synthesized compounds were tested for in vitro …
In silico designing of multiepitope-based-peptide (MBP) vaccine against MAPK protein express for Alzheimer's disease in Zebrafish
Understanding the role of the mitogen-activated protein kinases (MAPKs) signalling pathway
is essential in advancing treatments for neurodegenerative disorders like Alzheimer's. In this …
is essential in advancing treatments for neurodegenerative disorders like Alzheimer's. In this …