Cholangiocarcinoma (CCA) is a malignant tumour arising from the biliary system. In Europe,
this tumour frequently presents as a sporadic cancer in patients without defined risk factors …

Simple Summary Cholangiocarcinoma (CCA) is a heterogenous and aggressive
malignancy of the intra-and extrahepatic biliary tract, marked by a steeply rising incidence …

Abstract Background Isocitrate dehydrogenase 1/2 (IDH1/2), BAP1, ARID1A and PBRM1
have been reported as the most frequent mutant genes in intrahepatic cholangiocarcinoma …

The perineural invasion (PNI), which refers to tumor cells encroaching on nerve, is a clinical
feature frequently occurred in various malignant tumors, and responsible for postoperative …

Background In this study, we integrated single-cell RNA sequencing (scRNA-seq) data to
investigate cell heterogeneity and utilized MSigDB and CIBERSORTx to explore the …

Objectives Intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis and often
demonstrates an anti-apoptotic landscape, which is a key step to chemotherapy resistance …

Cholangiocarcinoma (CCA) is an aggressive malignancy with a 5‑year‑survival rate of<
10%, mainly due to diagnosis in advanced stages and limited therapeutic options in case of …

Background Digestive system cancers (DSCs) are associated with high morbidity and
mortality. S100P has been reported as a prognostic biomarker in DSCs, but its prognostic …

Background Malignant pleural mesothelioma (MPM) is an aggressive disease, with few
available treatment options. Identification of novel prognostic and predictive biomarkers is a …

The article discusses about the study conducted to determine nuclear BAP1
immunoexpression independent of the BRAF V600E status through Ameloblastoma. Topics …