Role of TRP ion channels in cancer and tumorigenesis
G Shapovalov, A Ritaine, R Skryma… - Seminars in …, 2016 - Springer
Transient receptor potential (TRP) channels are recently identified proteins that form a
versatile family of ion channels, the majority of which are calcium permeable and exhibit …
versatile family of ion channels, the majority of which are calcium permeable and exhibit …
TRPM channels in human diseases
The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
Integration of copy number and transcriptomics provides risk stratification in prostate cancer: a discovery and validation cohort study
Background Understanding the heterogeneous genotypes and phenotypes of prostate
cancer is fundamental to improving the way we treat this disease. As yet, there are no …
cancer is fundamental to improving the way we treat this disease. As yet, there are no …
[HTML][HTML] Functional and physiopathological implications of TRP channels
T Smani, G Shapovalov, R Skryma… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Abstract Transient Receptor Potential (TRP) channel proteins are a diverse family of proteins
that are expressed in many organisms, tissues and cell types. TRP channels respond to a …
that are expressed in many organisms, tissues and cell types. TRP channels respond to a …
Identification of potential crucial genes associated with the pathogenesis and prognosis of endometrial cancer
L Liu, J Lin, H He - Frontiers in genetics, 2019 - frontiersin.org
Background and Objective Endometrial cancer (EC) is a common gynecological malignancy
worldwide. Despite advances in the development of strategies for treating EC, prognosis of …
worldwide. Despite advances in the development of strategies for treating EC, prognosis of …
A novel Ca2+-mediated cross-talk between endoplasmic reticulum and acidic organelles: Implications for NAADP-dependent Ca2+ signalling
V Ronco, DM Potenza, F Denti, S Vullo, G Gagliano… - Cell Calcium, 2015 - Elsevier
Nicotinic acid adenine dinucleotide phosphate (NAADP) serves as the ideal trigger of spatio-
temporally complex intracellular Ca 2+ signals. However, the identity of the intracellular Ca …
temporally complex intracellular Ca 2+ signals. However, the identity of the intracellular Ca …
TRPM 4 regulates Akt/GSK 3‐β activity and enhances β‐catenin signaling and cell proliferation in prostate cancer cells
Increased expression of the TRPM 4 channel has been reported to be associated with the
progression of prostate cancer. However, the molecular mechanism underlying its effect …
progression of prostate cancer. However, the molecular mechanism underlying its effect …
Trpm4 in cancer—a new potential drug target
A Borgström, C Peinelt, P Stokłosa - Biomolecules, 2021 - mdpi.com
Transient receptor potential melastatin 4 (TRPM4) is widely expressed in various organs
and associated with cardiovascular and immune diseases. Lately, the interest in studies on …
and associated with cardiovascular and immune diseases. Lately, the interest in studies on …
Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans
The transient receptor potential melastatin (TRPM) protein family is an extensive group of
ion channels expressed in several types of mammalian cells. Many studies have shown that …
ion channels expressed in several types of mammalian cells. Many studies have shown that …
TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines
AI Sagredo, EA Sagredo, V Pola… - Journal of Cellular …, 2019 - Wiley Online Library
Abstract Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
dependent monovalent cation channel, which depolarizes the plasma cell membrane …