[HTML][HTML] Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Gene regulation and transcriptomics

DS Samuels, MC Lybecker, XF Yang, Z Ouyang… - Current issues in …, 2021 - mdpi.com
Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …

[HTML][HTML] Multifunctional and Redundant Roles of Borrelia burgdorferi Outer Surface Proteins in Tissue Adhesion, Colonization, and Complement Evasion

JA Caine, J Coburn - Frontiers in immunology, 2016 - frontiersin.org
Borrelia burgdorferi is the causative agent of Lyme disease in the US, with at least 25,000
cases reported to the CDC each year. B. burgdorferi is thought to enter and exit the …

[HTML][HTML] The emerging role of microbial biofilm in lyme neuroborreliosis

EG Di Domenico, I Cavallo, V Bordignon… - Frontiers in …, 2018 - frontiersin.org
Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete
Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and …

Regulation of gene and protein expression in the Lyme disease spirochete

B Stevenson, J Seshu - Spirochete Biology: The Post Genomic Era, 2018 - Springer
The infectious cycle of Borrelia burgdorferi necessitates persistent infection of both
vertebrates and ticks, and efficient means of transmission between those two very different …

Genetic Manipulation of Borrelia Spp.

D Drecktrah, DS Samuels - Spirochete Biology: The Post Genomic Era, 2018 - Springer
Abstract The spirochetes Borrelia (Borreliella) burgdorferi and Borrelia hermsii, the etiologic
agents of Lyme disease and relapsing fever, respectively, cycle in nature between an …

[HTML][HTML] In Vivo Imaging Demonstrates That Borrelia burgdorferi ospC Is Uniquely Expressed Temporally and Spatially throughout Experimental Infection

JT Skare, DK Shaw, JP Trzeciakowski, JA Hyde - PloS one, 2016 - journals.plos.org
Borrelia burgdorferi is a spirochetal bacterium transmitted by the Ixodes tick that causes
Lyme disease in humans due to its ability to evade the host immune response and …

BadR (BB0693) controls growth phase‐dependent induction of rpoS and bosR in Borrelia burgdorferi via recognizing TAAAATAT motifs

Z Ouyang, J Zhou - Molecular Microbiology, 2015 - Wiley Online Library
In B orrelia burgdorferi (B b), the alternative sigma factor RpoS plays a central role during
Bb's adaptation to ticks and mammals. Previous studies have demonstrated that RpoS is not …

Enzootic origins for clinical manifestations of Lyme borreliosis

S Jahfari, A Krawczyk, EC Coipan, M Fonville… - Infection, Genetics and …, 2017 - Elsevier
Both early localized and late disseminated forms of Lyme borreliosis are caused by Borrelia
burgdorferi senso lato. Differentiating between the spirochetes that only cause localized skin …

[HTML][HTML] Investigation of ospC Expression Variation among Borrelia burgdorferi Strains

X Xiang, Y Yang, J Du, T Lin, T Chen… - Frontiers in cellular and …, 2017 - frontiersin.org
Outer surface protein C (OspC) is the most studied major virulence factor of Borrelia
burgdorferi, the causative agent of Lyme disease. The level of OspC varies dramatically …