Malignant bone tumors, which are difficult to treat with current clinical strategies, originate
from bone tissues and can be classified into primary and secondary types. Due to the …

Metastatic bone disease occurs in 70–80% of advanced breast cancer patients and bone
tissue is accepted to have attractive physical properties that facilitate cancer cell attraction …

Bone is a biological tissue characterized by its hierarchical organization. This material has
the ability to be continually renewed, which makes it highly adaptative to external loadings …

Bone cells contribute to tumour metastasis by producing biochemical factors that stimulate
tumour cell homing and proliferation, but also by resorbing bone matrix (osteolysis) that …

Bone metastatic breast cancer is a malignant tumor in bone due to the metastasis of breast
cancer, and its incidence is increasing worldwide. Treatment of cancer metastasized to bone …

Tumor invasion into bone tissue during metastasis alters the biomechanical cues
experienced by both tumor and native bone cells. These cues may drive bone lysis and …

Breast cancer metastasises to bone in 70–80% of patients with advanced disease. Bone
cells contribute to tumour metastasis by activating bone resorption, which releases …

Остеосаркома позвоночника являются одним из видов рака приводящих к быстрой
инвалидизации человека. При этом считается, что поток интерстициальной жидкости в …