Learning Objectives After completing this course, the reader will be able to: Identify the
clinical factors that predict survival after a diagnosis of brain metastasis. Select appropriate …

Brain metastases are an important sequelae of many types of cancer, most commonly lung
cancer. Current treatment options include whole-brain radiation therapy (WBRT), surgical …

Motivation: The emergence of network medicine not only offers more opportunities for better
and more complete understanding of the molecular complexities of diseases, but also …

Background: Brain metastases are a common occurrence in patients with non-small-cell
lung cancer (NSCLC). Whole-brain radiotherapy (WBRT) is the standard therapy; more …

There is no accepted standard of care for the chemotherapy treatment of metastatic brain
tumors, which has been generally limited to lipophilic alkylators, which may not have efficacy …

Lung cancer is characterized by the highest incidence of solid tumor-related brain
metastases, which are reported with a growing incidence during the last decade. Prognostic …

Brain metastases are a frequent complication in patients suffering from lung cancer, and a
significant cause of morbidity and mortality. Brain metastases are found in about 10% of …

PURPOSE: To evaluate the safety profile and efficacy of whole brain radiotherapy (WBRT)
concomitantly with temozolomide (TMZ) in patients with brain metastases (BM). METHODS …

This review focuses on the management of brain metastases. The four main modes of
therapy are discussed: whole brain radiation therapy (WBRT), surgery, radiosurgery, and …

Brain metastases are the most common intracranial tumors and their incidence is increasing.
Untreated brain metastases are associated with a poor prognosis and a poor performance …