Radiopharmaceutical therapy in cancer: clinical advances and challenges
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …
Current status of theranostics in prostate cancer
The aim of this review is to report on the current status of prostate-specific membrane
antigen (PSMA)-directed theranostics in prostate cancer (PC) patients. The value of 68 Ga …
antigen (PSMA)-directed theranostics in prostate cancer (PC) patients. The value of 68 Ga …
Targeted α-therapy of metastatic castration-resistant prostate cancer with 225Ac-PSMA-617: dosimetry estimate and empiric dose finding
C Kratochwil, F Bruchertseifer, H Rathke… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The aim of this study was to develop a treatment protocol for 225Ac-PSMA-617 α-radiation
therapy in advanced-stage, metastatic castration-resistant prostate cancer patients with …
therapy in advanced-stage, metastatic castration-resistant prostate cancer patients with …
Targeted radionuclide therapy of prostate cancer—from basic research to clinical perspectives
M Czerwińska, A Bilewicz, M Kruszewski… - Molecules, 2020 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men and the second
leading cause of cancer-related deaths in Western civilization. Although localized prostate …
leading cause of cancer-related deaths in Western civilization. Although localized prostate …
A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
J Zhang, A Rakhimbekova, X Duan, Q Yin… - Nature …, 2021 - nature.com
Surgery is an efficient way to treat localized prostate cancer (PCa), however, it is challenging
to demarcate rapidly and accurately the tumor boundary intraoperatively, as existing tumor …
to demarcate rapidly and accurately the tumor boundary intraoperatively, as existing tumor …
[HTML][HTML] Advances in PSMA theranostics
TM Jeitner, JW Babich, JM Kelly - Translational Oncology, 2022 - Elsevier
The validation of prostate specific membrane antigen (PSMA) as a molecular target in
metastatic castration-resistant prostate cancer has stimulated the development of multiple …
metastatic castration-resistant prostate cancer has stimulated the development of multiple …
[HTML][HTML] Prostate-specific membrane antigen as a target for cancer imaging and therapy
The prostate-specific membrane antigen (PSMA) is a molecular target whose use has
resulted in some of the most productive work toward imaging and treating prostate cancer …
resulted in some of the most productive work toward imaging and treating prostate cancer …
Targeting prostate cancer: prostate‐specific membrane antigen based diagnosis and therapy
T Wüstemann, U Haberkorn, J Babich… - Medicinal research …, 2019 - Wiley Online Library
The high incidence rates of prostate cancer (PCa) raise demand for improved therapeutic
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …
Preclinical development of novel PSMA-targeting radioligands: modulation of albumin-binding properties to improve prostate cancer therapy
CA Umbricht, M Benesova, R Schibli… - Molecular …, 2018 - ACS Publications
The treatment of metastatic castration-resistant prostate cancer (mCRPC) remains
challenging with current treatment options. The development of more effective therapies is …
challenging with current treatment options. The development of more effective therapies is …
The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research
EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …
and development of prostate cancer (PCa) imaging and therapeutic strategies using …