Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

The endothelial angiopoietin (ANG)–TIE growth factor receptor pathway regulates vascular
permeability and pathological vascular remodelling during inflammation, tumour …

Microvascular endothelial cells in the kidney have been a neglected cell type in sepsis-
induced acute kidney injury (sepsis-AKI) research; yet, they offer tremendous potential as …

The angiopoietin/Tie (ANG/Tie) receptor system controls developmental and tumor
angiogenesis, inflammatory vascular remodeling, and vessel leakage. ANG1 is a Tie2 …

Angiopoietins regulate vascular homeostasis via the endothelial Tie receptor tyrosine
kinases. Angiopoietin-1 (Ang1) supports endothelial stabilization via Tie2 activation …

Endothelial cells that form the inner layer of blood and lymphatic vessels are important
regulators of vascular functions and centrally involved in the pathogenesis of vascular …

Sepsis, a dysregulated host response to infection that causes life-threatening organ
dysfunction, is a highly heterogeneous syndrome with no specific treatment. Although sepsis …

Angiopoietins and Tie2 in vascular inflammation : Current Opinion in Hematology Angiopoietins
and Tie2 in vascular inflammation : Current Opinion in Hematology Log in or Register …

Ligands of the endothelial-enriched tunica interna endothelial cell kinase 2 (Tie2) are
markedly imbalanced in severe infections associated with vascular leakage, yet regulation …

Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus
(DENV) infection, but the mechanisms underlying the exacerbated inflammation during …