Nanoadjuvants: promising bioinspired and biomimetic approaches in vaccine innovation
Adjuvants are the important part of vaccine manufacturing as they elicit the vaccination effect
and enhance the durability of the immune response through controlled release. In light of …
and enhance the durability of the immune response through controlled release. In light of …
Nanovaccines for cancer immunotherapy: Focusing on complex formation between adjuvant and antigen
NH Goradel, M Nemati, A Bakhshandeh… - International …, 2023 - Elsevier
As an interesting cancer immunotherapy approach, cancer vaccines have been developed
to deliver tumor antigens and adjuvants to antigen-presenting cells (APCs). Although the …
to deliver tumor antigens and adjuvants to antigen-presenting cells (APCs). Although the …
Adjuvanted quaternized chitosan composite aluminum nanoparticles-based vaccine formulation promotes immune responses in chickens
J Liu, S Guo, Z Jin, K Zhao - Vaccine, 2023 - Elsevier
Aluminum adjuvant is a typical adjuvant that can promote humoral immune response, but it
lacks the ability to effectively induce cellular immune response. The water-soluble N-2 …
lacks the ability to effectively induce cellular immune response. The water-soluble N-2 …
Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018TM Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 …
Aluminum-salt vaccine adjuvants (alum) are commercially available as micron-sized
particles with varying chemical composition and crystallinity. There are reports of enhanced …
particles with varying chemical composition and crystallinity. There are reports of enhanced …
Effect of aluminium oxide nanoparticles on long-acting oleogels laden with Sc-PLA-chitosan nanoparticles for anti-HIV therapy
VHB Narayanan, R Durai, W Gonciarz… - International Journal of …, 2024 - Elsevier
The development of a long-acting injectable drug delivery system of active pharmaceutical
ingredients (API) holds great promise in addressing the challenges of treatment adherence …
ingredients (API) holds great promise in addressing the challenges of treatment adherence …
Nanoscale alum-based adjuvants: Current status and future prospects
The effectiveness of vaccines can be greatly enhanced by using nanomaterials in
formulation strategies. One example of this strategy is the modification of vaccine adjuvants …
formulation strategies. One example of this strategy is the modification of vaccine adjuvants …
Aluminum Oxide Nanoparticles: Properties and Applications Overview
RC Congreve, CP Quezada… - Nanoparticles in Modern …, 2024 - Springer
Aluminum oxide nanoparticles (Al2O3 NPs) have attracted significant attention to various
scientific and industrial fields due to their unique bio−/physicochemical properties: high …
scientific and industrial fields due to their unique bio−/physicochemical properties: high …
An investigation on microfluidic preparation of aluminum phosphate adjuvant
C Yuan, Q Gu, H Fang, H Xia - Microfluidics and Nanofluidics, 2023 - Springer
Aluminum adjuvants have been used for almost a century due to their good record of safety
and efficacy. However, their preparation is rather traditional and usually exhibits batch-to …
and efficacy. However, their preparation is rather traditional and usually exhibits batch-to …
Evaluation of Aluminium Hydroxide Nanoparticles as an Efficient Adjuvant to Potentiate the Immune Response against Clostridium botulinum Serotypes C and D …
Z Mbhele, L Thwala, T Khoza, F Ramagoma - Vaccines, 2023 - mdpi.com
Clostridium botulinum serotypes C and D cause botulism in livestock, a neuroparalytic
disease that results in substantial economic losses. Vaccination with aluminium-based …
disease that results in substantial economic losses. Vaccination with aluminium-based …
疫苗佐剂的作用机制及研究进展
张丽， 卢畅， 安明惠， 王萌萌， 宗晓郁… - 中国临床药理学 …, 2024 - manu41.magtech.com.cn
疫苗是预防传染性疾病最有效的措施之一, 对预防及控制传染病的传播起到了重要作用.
而佐剂作为疫苗的辅助成分, 在疫苗研发过程中不可或缺. 理想的佐剂不仅可以增强免疫反应 …
而佐剂作为疫苗的辅助成分, 在疫苗研发过程中不可或缺. 理想的佐剂不仅可以增强免疫反应 …