Modulating epigenetic modifications for cancer therapy

LJ Castro-Muñoz, E Vázquez Ulloa… - Oncology …, 2023 - spandidos-publications.com
Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …

Green tea polyphenols-derived hybrid materials in manufacturing, environment, food and healthcare

C Xu, S Zhou, H Song, H Hu, Y Yang, X Zhang, S Ma… - Nano Today, 2023 - Elsevier
Tea, as a well-known medicinal beverage, has gained a widespread reputation for its
remarkable health benefits. Among various constituents in tea, tea polyphenols (TPs) stand …

Engineering polyphenol-based polymeric nanoparticles for drug delivery and bioimaging

X Wang, Y Fan, J Yan, M Yang - Chemical Engineering Journal, 2022 - Elsevier
Polyphenols are compounds with phenolic hydroxyl groups that are widely found in natural
plants. The beneficial effects of polyphenols have been studied extensively, especially anti …

Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …

Antibacterial and antifungal properties of silver nanoparticles—effect of a surface-stabilizing agent

A Gibała, P Żeliszewska, T Gosiewski, A Krawczyk… - Biomolecules, 2021 - mdpi.com
The biocidal properties of silver nanoparticles (AgNPs) prepared with the use of biologically
active compounds seem to be especially significant for biological and medical application …

An injectable co-assembled hydrogel blocks reactive oxygen species and inflammation cycle resisting myocardial ischemia-reperfusion injury

X Liao, X Song, J Li, L Li, X Fan, Q Qin, C Zhong… - Acta biomaterialia, 2022 - Elsevier
The overproduction of reactive oxygen species (ROS) and burst of inflammation following
cardiac ischemia–reperfusion (I/R) are the leading causes of cardiomyocyte injury …

Ferulic acid: a promising therapeutic phytochemical and recent patents advances

A Chaudhary, VS Jaswal, S Choudhary… - Recent Patents on …, 2019 - benthamdirect.com
Background: Among the various phenolics metabolites, ferulic acid is considered as the
promising mitigating, restorative and antioxidant agent. Ferulic acid is one of the most …

Epigallocatechin-3-gallate therapeutic potential in cancer: mechanism of action and clinical implications

M Kciuk, M Alam, N Ali, S Rashid, P Głowacka… - Molecules, 2023 - mdpi.com
Cellular signaling pathways involved in the maintenance of the equilibrium between cell
proliferation and apoptosis have emerged as rational targets that can be exploited in the …

Epigallocatechin‐3‐gallate attenuates microglial inflammation and neurotoxicity by suppressing the activation of canonical and noncanonical inflammasome via TLR4 …

X Zhong, M Liu, W Yao, K Du, M He… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope In this study, it has been investigated whether the neuroprotective efficacy of
epigallocatechin‐3‐gallate (EGCG) is mediated by inhibition of canonical and noncanonical …

Effects of flavonoids and its derivatives on immune cell responses

G Martínez, MR Mijares… - Recent Patents on …, 2019 - ingentaconnect.com
Background: Various pieces of evidence have shown that people who consume foods rich in
polyphenolic and flavonoids compounds have a lower incidence of inflammatory …