Electron transfer flavoprotein (ETF) is an enzyme with orthologs from bacteria to humans.
Human ETF is nuclear encoded by two separate genes, ETFA and ETFB, respectively. After …

Mitochondria play a key role in overall cell physiology and health by integrating cellular
metabolism with cellular defense and repair mechanisms in response to physiological or …

The role of lipids in providing energy and structural cellular components during vertebrate
development is poorly understood. To elucidate these roles further, we visualized lipid …

Riboflavin, commonly known as vitamin B2, is the precursor of flavin cofactors. It is present in
our typical diet, and inside the cells it is metabolized to FMN and FAD. As a result of their …

Mitochondrial fatty acid β-oxidation disorders (FAODs) are a group of about 20 diseases
which are caused by specific mutations in genes that codify proteins or enzymes involved in …

This review discusses why the embryo requires vitamin E (VitE) and shows that its lack
causes metabolic dysregulation and impacts morphological changes at very early stages in …

Lipid storage myopathies (LSMs) are a heterogeneous group of genetic disorders that
present with abnormal lipid storage in multiple body organs, typically muscle. Patients can …

Background and Purpose Mitochondria are a drug target in mitochondrial dysfunction
diseases and in antiparasitic chemotherapy. While zebrafish is increasingly used as a …

Multiple acyl-coenzyme A dehydrogenase deficiency (MADD), or glutaric aciduria type II
(GAII), is a group of clinically heterogeneous disorders caused by mutations in electron …

Inhabitants of the marine rocky intertidal live in an environment that alternates between
aquatic and terrestrial due to the rise and fall of the tide. The tide creates a cyclical …