The neuroprotective effect of vitamin D in Parkinson's disease: association or causation
AA Hafiz - Nutritional neuroscience, 2024 - Taylor & Francis
Parkinson's disease (PD) is a chronic neurodegenerative disease (NDD) due to the
degeneration of dopaminergic neurons (DNs) in the substantia nigra (SN). PD is …
degeneration of dopaminergic neurons (DNs) in the substantia nigra (SN). PD is …
[HTML][HTML] Metabolic reprogramming in inflammatory microglia indicates a potential way of targeting inflammation in Alzheimer's disease
M Sangineto, M Ciarnelli, T Cassano, A Radesco… - Redox biology, 2023 - Elsevier
Microglia activation drives the pro-inflammatory activity in the early stages of Alzheimer's
disease (AD). However, the mechanistic basis is elusive, and the hypothesis of targeting …
disease (AD). However, the mechanistic basis is elusive, and the hypothesis of targeting …
Vitamin D, a secosteroid hormone and its multifunctional receptor, vitamin D receptor, in Alzheimer's type neurodegeneration
D Gezen-Ak, E Dursun - J Alzheimers Dis, 2023 - content.iospress.com
Vitamin D is a secosteroid hormone exerting neurosteroid-like properties. Its well-known
nuclear hormone receptor, and recently proposed as a mitochondrial transcription factor …
nuclear hormone receptor, and recently proposed as a mitochondrial transcription factor …
Regulation of neuroinflammation in Alzheimer's disease via nanoparticle-loaded phytocompounds with anti-inflammatory and autophagy-inducing properties
Background Alzheimer's disease (AD) is characterized by neuroinflammation linked to
amyloid β (Aβ) aggregation and phosphorylated tau (τ) protein in neurofibrillary tangles …
amyloid β (Aβ) aggregation and phosphorylated tau (τ) protein in neurofibrillary tangles …
Changes Induced by P2X7 Receptor Stimulation of Human Glioblastoma Stem Cells in the Proteome of Extracellular Vesicles Isolated from Their Secretome
F Di Giuseppe, L Ricci-Vitiani, R Pallini, R Di Pietro… - Cells, 2024 - mdpi.com
Extracellular vesicles (EVs) are secreted from many tumors, including glioblastoma
multiforme (GBM), the most common and lethal brain tumor in adults, which shows high …
multiforme (GBM), the most common and lethal brain tumor in adults, which shows high …
[HTML][HTML] The Role of Gene Expression Dysregulation in the Pathogenesis of Mucopolysaccharidosis: A Comparative Analysis of Shared and Specific Molecular …
K Wiśniewska, M Żabińska, A Szulc, L Gaffke… - International Journal of …, 2024 - mdpi.com
Mucopolysaccharidosis (MPS) comprises a group of inherited metabolic diseases. Each
MPS type is caused by a deficiency in the activity of one kind of enzymes involved in …
MPS type is caused by a deficiency in the activity of one kind of enzymes involved in …
Hypoxic preconditioned neural stem cell-derived extracellular vesicles contain distinct protein cargo from their normal counterparts
Hypoxic preconditioning has been demonstrated to increase the resistance of neural stem
cells (NSCs) to hypoxic conditions, as well as to improve their capacity for differentiation and …
cells (NSCs) to hypoxic conditions, as well as to improve their capacity for differentiation and …
A comprehensive multi-omics signature of doxorubicin-induced cellular senescence in the postmenopausal human ovary.
A major aging hallmark is the accumulation of cellular senescence burden. Over time
senescent cells contribute to tissue deterioration through chronic inflammation and fibrosis …
senescent cells contribute to tissue deterioration through chronic inflammation and fibrosis …
Experimental and Computational Approaches to Control Mammalian Cell Proliferation, Protein Production, and Post-translational Modifications
L Mao - 2023 - search.proquest.com
Therapeutic antibodies, with their high specificity and flexibility, are responsible for treating
many acute and chronic diseases. In particular, monoclonal antibodies remain the largest …
many acute and chronic diseases. In particular, monoclonal antibodies remain the largest …