Zebrafish behavior: opportunities and challenges

MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

The art and design of genetic screens: zebrafish

EE Patton, LI Zon - Nature Reviews Genetics, 2001 - nature.com
Inventive genetic screens in zebrafish are revealing new genetic pathways that control
vertebrate development, disease and behaviour. By exploiting the versatility of zebrafish …

Structure of the zebrafish locomotor repertoire revealed with unsupervised behavioral clustering

JC Marques, S Lackner, R Félix, MB Orger - Current Biology, 2018 - cell.com
An important concept in ethology is that complex behaviors can be constructed from a set of
basic motor patterns. Identifying the set of patterns available to an animal is key to making …

A genetic screen for mutations affecting embryogenesis in zebrafish

W Driever, L Solnica-Krezel, AF Schier… - …, 1996 - journals.biologists.com
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been
instrumental in the understanding of invertebrate and plant development. Here, we report …

[图书][B] Zebrafish

C Nusslein-Volhard, R Dahm - 2002 - books.google.com
The zebrafish has become one of the most important model organisms to study biologial
processes in vivo. As a vertebrate that has many of the strengths of invertebrate model …

Modulation of locomotor activity in larval zebrafish during light adaptation

HA Burgess, M Granato - Journal of Experimental Biology, 2007 - journals.biologists.com
The neural basis of behavioral choice in vertebrates remains largely unknown. Zebrafish
larvae have a defined locomotor repertoire as well as a simple nervous system and are …

[HTML][HTML] Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior

R Portugues, CE Feierstein, F Engert, MB Orger - Neuron, 2014 - cell.com
Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …

Locomotor repertoire of the larval zebrafish: swimming, turning and prey capture

SA Budick, DM O'Malley - Journal of Experimental Biology, 2000 - journals.biologists.com
Larval zebrafish (Brachydanio rerio) are a popular model system because of their genetic
attributes, transparency and relative simplicity. They have approximately 200 neurons that …

Early retinal development in the zebrafish, Danio rerio: Light and electron microscopic analyses

EA Schmitt, JE Dowling - Journal of Comparative Neurology, 1999 - Wiley Online Library
The morphological differentiation of the zebrafish retina was analyzed by using light (LM)
and transmission electron (TEM) microscopy between the time of initial ganglion cell …

A large-scale insertional mutagenesis screen in zebrafish

A Amsterdam, S Burgess, G Golling… - Genes & …, 1999 - genesdev.cshlp.org
It is estimated that∼ 2500 genes are essential for the normal development of a zebrafish
embryo. A mutation in any one of these genes can result in a visible developmental defect …